Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …

Autophagy is a self‐digestive process that degrades intracellular components, including
damaged organelles, to maintain energy homeostasis and to cope with cellular stress …

Cancer is a complex disorder extremely dependent on its microenvironment and highly
regulated by multiple intracellular and extracellular stimuli. Studies show that reactive …

Insulin, which is released by pancreatic islet β-cells in response to elevated levels of
glucose in the blood, is a critical regulator of metabolism. Insulin triggers the uptake of …

Metabolic plasticity, which determines tumour growth and metastasis, is now understood to
be a flexible and context-specific process in cancer metabolism. One of the major pathways …

Nitric oxide (NO) and hydrogen sulfide (H 2 S) are the key gasotransmitters with an
imperious role in the maintenance of cerebrovascular homeostasis. A decline in their levels …

S-nitrosylation is a selective and reversible post-translational modification of protein thiols by
nitric oxide (NO), which is a bioactive signaling molecule, to exert a variety of effects. These …

Obesity is associated with elevated intracellular nitric oxide (NO) production, which
promotes nitrosative stress in metabolic tissues such as liver and skeletal muscle …

Significance: Most brains affected by neurodegenerative diseases manifest mitochondrial
dysfunction as well as elevated production of reactive oxygen species and reactive nitrogen …

Diabetes cardiomyopathy has metabolic disorder and abnormality of cardiomyocytes, which
is closely related to autophagy or apoptosis of cardiomyocytes. Scutellarin (SCU) is an …