Clinical application of biological agents in rheumatoid arthritis

L Cheng, X Rong - Transplant Immunology, 2025 - Elsevier
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disorder primarily
distinguished by synovial inflammation, which, as the disease evolves, can lead to bone …

Generation and characterization of OX40-ligand fusion protein that agonizes OX40 on T-Lymphocytes

A Sato, H Nagai, A Suzuki, A Ito, S Matsuyama… - Frontiers in …, 2025 - frontiersin.org
OX40, a member of the tumor necrosis factor (TNF) receptor superfamily, is expressed on
the surface of activated T cells. Upon interaction with its cognate ligand, OX40L, OX40 …