Hypertension is associated with immune cells activation and their migration into the kidney,
vasculature, heart and brain. These inflammatory mechanisms are critical for blood pressure …

Taurine is a non-protein amino acid that is expressed in the majority of animal tissues. With
its unique sulfonic acid makeup, taurine influences cellular functions, including …

Milk-derived extracellular vesicles (mEVs) have been proposed as a potential nanomedicine
for intestinal disorders; however, their impact on intestinal barrier integrity in gut …

Objective: This study aimed to explore the role of circular RNAs (circRNAs) in M2
macrophage (M2M)-derived small extracellular vesicles (SEVs) in myocardial fibrosis …

In the setting of myocardial infarction (MI), ischemia reperfusion injury (IRI) occurs due to
occlusion (ischemia) and subsequent re-establishment of blood flow (reperfusion) of a …

In the infarcted myocardium, cardiomyocyte necrosis triggers an intense inflammatory
reaction that not only is critical for cardiac repair, but also contributes to adverse remodeling …

Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality
globally. The emerging role of extracellular vesicles (EVs) in intercellular communication …

Atherosclerosis is a chronic inflammatory vascular disease that is characterized by the
accumulation of lipids and immune cells in plaques built up inside artery walls …

Cardiovascular disease (CVD) is the major leading cause of morbidity and mortality
worldwide. According to the pro-inflammatory nature of CVD, recent studies highlighted the …

The adult mammalian heart has limited endogenous regenerative capacity and heals
through the activation of inflammatory and fibrogenic cascades that ultimately result in the …