Collagen VI represents a remarkable extracellular matrix molecule, and in the past few
years, studies of this molecule have revealed its involvement in a wide range of tissues and …

Basement membranes are widely distributed extracellular matrices that coat the basal
aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells …

The extracellular matrix (ECM) of blood vessels, which is composed of both the vascular
basement membrane (BM) and the interstitial ECM is identified as a crucial component of …

The von Willebrand A (VWA) domain is a well-studied domain involved in cell adhesion, in
extracellular matrix proteins, and in integrin receptors. A number of human diseases arise …

The deleterious age-related changes in collagen that manifest in the stiffening of the joints,
the vascular system and the renal and retinal capillaries are primarily due to the …

Human skin consists of a stratified, cellular epidermis and an underlying dermis of
connective tissue [1–5]. The dermal–epidermal junction is undulating in section; ridges of …

Background: Idiopathic epiretinal membrane (iERM) is a fibrocellular membrane that
proliferates on the inner surface of the retina at the macular area. Membrane contraction is …

Collagen VI is an extracellular matrix protein that forms a microfilamentous network in
skeletal muscles and other organs,,. Inherited mutations in genes encoding collagen VI in …

Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and
idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) …

The collagen VI-related myopathy known as Ullrich congenital muscular dystrophy is an
early-onset disease that combines substantial muscle weakness with striking joint laxity and …