Anticancer perspective of 6-shogaol: Anticancer properties, mechanism of action, synergism and delivery system

Y Jia, X Li, X Meng, J Lei, Y Xia, L Yu - Chinese Medicine, 2023 - Springer
Cancer is a malignant disease that has plagued human beings all the time, but the treatment
effect of commonly used anticancer drugs in clinical practice is not ideal by reason of their …

The anti-leukemic activity of natural compounds

C Cotoraci, A Ciceu, A Sasu, E Miutescu, A Hermenean - Molecules, 2021 - mdpi.com
The use of biologically active compounds has become a realistic option for the treatment of
malignant tumors due to their cost-effectiveness and safety. In this review, we aimed to …

[HTML][HTML] Biological evaluation of combinations of tyrosine kinase inhibitors with Inecalcitol as novel treatments for human chronic myeloid leukemia

L Al-Ali, RJ Al-Ani, MM Saleh, AM Hammad… - Saudi Pharmaceutical …, 2024 - Elsevier
Background The use of tyrosine kinase inhibitors (TKIs) as a treatment for chronic myeloid
leukemia (CML) has improved the natural history of the disease and increased the duration …

Influence of 6-shogaol potentiated on 5-fluorouracil treatment of liver cancer by promoting apoptosis and cell cycle arrest by regulating AKT/mTOR/MRP1 signalling

Y Zhang, QU Yong, C Yun-Zhong - Chinese Journal of Natural Medicines, 2022 - Elsevier
Currently, chemoresistance seriously attenuates the curative outcome of liver cancer. The
purpose of our work was to investigate the influence of 6-shogaol on the inhibition of 5 …

Combination treatments of imatinib with astaxanthin and crocin efficiently ameliorate antioxidant status, inflammation and cell death progression in imatinib-resistant …

A Golestani, A Rahimi, M Najafzadeh, M Sayadi… - Molecular Biology …, 2024 - Springer
Background Imatinib resistance remains a major obstacle in the treatment of chronic
myelogenous leukemia (CML). Crocin (CRC) and astaxanthin (ATX) are phytochemicals …

An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities

C Yang, W Chen, B Ye, K Nie - Food & Function, 2024 - pubs.rsc.org
Ginger (Zingiber officinale Roscoe) has traditionally been used as a cooking spice and
herbal medicine for treating nausea and vomiting. More recently, ginger was found to …

Synthesis of novel indol-3-acetamido analogues as potent anticancer agents, biological evaluation and molecular modeling studies

F Doganc, T Ozkan, N Farhangzad, A Mavideniz… - Bioorganic …, 2024 - Elsevier
Cannabinoids bind to cannabinoid receptors CB1 and CB2 and their antitumoral activity has
been reported against some various cancer cell lines. Some synthetic cannabinoids …

Targeting production of reactive oxygen species as an anticancer strategy

GK Marioli-Sapsakou, M Kourti - Anticancer Research, 2021 - ar.iiarjournals.org
Cancer remains the second leading cause of death worldwide. Research is currently
focused on finding novel anticancer therapies and elucidating their mechanisms of action …

Recent Advances in Natural Products with Anti-Leukemia and Anti-Lymphoma Activities

ZG Sun, CJ Yao, I Ullah, HL Zhu - Mini Reviews in Medicinal …, 2024 - ingentaconnect.com
Leukemia and lymphoma are the most common blood cancers, which pose a critical threat
to the health of adults and children. The total incidence and mortality rates of both are …

Identification of exosomal microRNAs and related hub genes associated with imatinib resistance in chronic myeloid leukemia

AZ Karabay, T Ozkan, A Karadag Gurel, A Koc… - Naunyn-Schmiedeberg's …, 2024 - Springer
Chemotherapy resistance is a major obstacle in cancer therapy, and identifying novel
druggable targets to reverse this phenomenon is essential. The exosome-mediated …