Cerebral organoids as an experimental platform for human neurogenomics

TJ Nowakowski, SR Salama - Cells, 2022 - mdpi.com
The cerebral cortex forms early in development according to a series of heritable
neurodevelopmental instructions. Despite deep evolutionary conservation of the cerebral …

From end to end: Gaining, sorting, and employing high-density neural single unit recordings

RB Bod, J Rokai, D Meszéna, R Fiáth… - Frontiers in …, 2022 - frontiersin.org
The meaning behind neural single unit activity has constantly been a challenge, so it will
persist in the foreseeable future. As one of the most sourced strategies, detecting neural …

IoT cloud laboratory: Internet of Things architecture for cellular biology

DF Parks, K Voitiuk, J Geng, MAT Elliott, MG Keefe… - Internet of Things, 2022 - Elsevier
Abstract The Internet of Things (IoT) provides a simple framework to control online devices
easily. IoT is now a commonplace tool used by technology companies but is rarely used in …

Internet-connected cortical organoids for project-based stem cell and neuroscience education

MAT Elliott, HE Schweiger, A Robbins… - eneuro, 2023 - eneuro.org
The introduction of Internet-connected technologies to the classroom has the potential to
revolutionize STEM education by allowing students to perform experiments in complex …

Reducing education inequalities through cloud-enabled live-cell biotechnology

S Vera-Choqqueccota, BEY Belmekki, MS Alouini… - Trends in …, 2024 - cell.com
Biotechnology holds the potential to drive innovations across various fields from agriculture
to medicine. However, despite numerous interventions, biotechnology education remains …

A feedback-driven IoT microfluidic, electrophysiology, and imaging platform for brain organoid studies

K Voitiuk, ST Seiler, MP de Melo, J Geng… - …, 2024 - pmc.ncbi.nlm.nih.gov
The analysis of tissue cultures, particularly brain organoids, takes a high degree of
coordination, measurement, and monitoring. We have developed an automated research …

Data analytics in a clinical setting: Applications to understanding breathing patterns and their relevance to neonatal disease

CG Wilson, AE Altamirano, T Hillman, JB Tan - Seminars in Fetal and …, 2022 - Elsevier
In this review, we focus on the use of contemporary linear and non-linear data analytics as
well as machine learning/artificial intelligence algorithms to inform treatment of pediatric …

Internet of things architecture for high throughput biology

DF Parks, K Voitiuk, J Geng, MAT Elliott, MG Keefe… - BioRxiv, 2021 - biorxiv.org
New cell culture techniques have led to complex tissue models in biological experiments.
For example, 3-D cerebral organoids provide a more realistic model of the human cortical …

Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization

J Geng, K Voitiuk, DF Parks, A Robbins, A Spaeth… - bioRxiv, 2024 - biorxiv.org
Electrophysiology offers a high-resolution method for real-time measurement of neural
activity. The vast amount of data generated requires efficient storage and sophisticated …

Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology

J Lumpuy-Castillo, Y Fu, A Ávila, K Solodka, J Li… - bioRxiv, 2024 - biorxiv.org
In vitro models have now become a realistic alternative to animal models for cardiotoxicity
assessment. However, the cost and expertise required to implement in vitro …