Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y12 Receptor Inhibitor Treatment in Percutaneous Coronary …

D Sibbing, D Aradi, D Alexopoulos, J Ten Berg… - JACC: Cardiovascular …, 2019 - jacc.org
Dual-antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the standard
treatment for patients undergoing percutaneous coronary intervention. The availability of …

The East Asian paradox: an updated position statement on the challenges to the current antithrombotic strategy in patients with cardiovascular disease

HK Kim, US Tantry, SC Smith Jr… - Thrombosis and …, 2021 - thieme-connect.com
East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during
antithrombotic therapies compared with Caucasian patients. As potent P2Y 12 receptor …

JCS 2018 guideline on diagnosis and treatment of acute coronary syndrome

K Kimura, T Kimura, M Ishihara, Y Nakagawa… - Circulation …, 2019 - jstage.jst.go.jp
Acute coronary syndromes (ACS) are a comprehensive disease concept characterized by
acute myocardial ischemia caused by disruption of coronary artery plaque and consequent …

JCS 2020 guideline focused update on antithrombotic therapy in patients with coronary artery disease

M Nakamura, K Kimura, T Kimura, M Ishihara… - Circulation …, 2020 - jstage.jst.go.jp
In 2019, the Japanese Circulation Society published 2 guidelines in the field of coronary
artery disease (CAD):(1) a guideline for acute coronary syndrome (ACS) that integrated …

Prasugrel-based de-escalation of dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (HOST-REDUCE …

HS Kim, J Kang, D Hwang, JK Han, HM Yang, HJ Kang… - The Lancet, 2020 - thelancet.com
Summary Background A potent P2Y12 inhibitor-based dual antiplatelet therapy is
recommended for up to 1 year in patients with acute coronary syndrome receiving …

Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary …

D Aradi, A Kirtane, L Bonello, PA Gurbel… - European heart …, 2015 - academic.oup.com
Aims Although platelet reactivity during P2Y12-inhibitors is associated with stent thrombosis
(ST) and bleeding, standardized and clinically validated thresholds for accurate risk …

Clinically significant bleeding with ticagrelor versus clopidogrel in Korean patients with acute coronary syndromes intended for invasive management: a randomized …

DW Park, O Kwon, JS Jang, SC Yun, H Park, DY Kang… - Circulation, 2019 - Am Heart Assoc
Background: Owing to the differential propensity for bleeding and ischemic events with
response to antiplatelet therapy, the safety and effectiveness of potent P2Y12 inhibitor …

Ticagrelor vs. clopidogrel in Japanese, Korean and Taiwanese patients with acute coronary syndrome–randomized, double-blind, phase III PHILO study–

S Goto, CH Huang, SJ Park, H Emanuelsson… - Circulation …, 2015 - jstage.jst.go.jp
Background: Few data on the relative efficacy and safety of new P2Y 12 inhibitors such as
prasugrel and ticagrelor in Japanese, Taiwanese and South Korean patients with acute …

Evolution of antithrombotic therapy in patients undergoing percutaneous coronary intervention: a 40-year journey

D Cao, R Chandiramani, M Chiarito… - European Heart …, 2021 - academic.oup.com
Since its introduction in 1977, percutaneous coronary intervention has become one of the
most commonly performed therapeutic procedures worldwide. Such widespread diffusion …

Prediction of thrombotic and bleeding events after percutaneous coronary intervention: CREDO‐Kyoto thrombotic and bleeding risk scores

M Natsuaki, T Morimoto, K Yamaji… - Journal of the …, 2018 - Am Heart Assoc
Background Prediction of thrombotic and bleeding risk is important to optimize
antithrombotic therapy after percutaneous coronary intervention. Methods and Results We …