Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

V Rani, G Deep, RK Singh, K Palle, UCS Yadav - Life sciences, 2016 - Elsevier
Increased body weight and metabolic disorder including insulin resistance, type 2 diabetes
and cardiovascular complications together constitute metabolic syndrome. The …

Obesity-associated oxidative stress: strategies finalized to improve redox state

I Savini, MV Catani, D Evangelista, V Gasperi… - International journal of …, 2013 - mdpi.com
Obesity represents a major risk factor for a plethora of severe diseases, including diabetes,
cardiovascular disease, non-alcoholic fatty liver disease, and cancer. It is often …

Obesity, metabolic syndrome, and primary hypertension

M Litwin, Z Kułaga - Pediatric Nephrology, 2021 - Springer
Primary hypertension is the dominant form of arterial hypertension in adolescents. Disturbed
body composition with, among other things, increased visceral fat deposition, accelerated …

The isoprostanes—25 years later

GL Milne, Q Dai, LJ Roberts II - … et Biophysica Acta (BBA)-Molecular and …, 2015 - Elsevier
Isoprostanes (IsoPs) are prostaglandin-like molecules generated independent of the
cyclooxygenase (COX) by the free radical-induced peroxidation of arachidonic acid. The first …

Obesity and atrial fibrillation: a narrative review from arrhythmogenic mechanisms to clinical significance

H Shu, J Cheng, N Li, Z Zhang, J Nie, Y Peng… - Cardiovascular …, 2023 - Springer
The prevalence of obesity and atrial fibrillation (AF), which are inextricably linked, is rapidly
increasing worldwide. Obesity rates are higher among patients with AF than healthy …

'Adipaging': ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue

LM Pérez, H Pareja‐Galeano… - The Journal of …, 2016 - Wiley Online Library
The increasing ageing of our societies is accompanied by a pandemic of obesity and related
cardiometabolic disorders. Progressive dysfunction of the white adipose tissue is …

Obesity and insulin resistance: associations with chronic inflammation, genetic and epigenetic factors

A Gasmi, S Noor, A Menzel, L Pivina… - Current medicinal …, 2021 - ingentaconnect.com
Background: Obesity is known to be a multifactorial disease. In its pathogenesis, different
factors such as chronic inflammation, oxidative stress, insulin resistance, genetic factors …

Role of magnesium in oxidative stress in individuals with obesity

JBS Morais, JS Severo, LR Santos… - Biological trace element …, 2017 - Springer
Adipose tissue is considered an endocrine organ that promotes excessive production of
reactive oxygen species when in excess, thus contributing to lipid peroxidation. Magnesium …

Oxidative stress in non-alcoholic fatty liver disease

C Smirne, E Croce, D Di Benedetto, V Cantaluppi… - Livers, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple
factors, which may partly explain why it still remains an orphan of adequate therapies. This …

Genetics of oxidative stress in obesity

AI Rupérez, A Gil, CM Aguilera - International journal of molecular …, 2014 - mdpi.com
Obesity is a multifactorial disease characterized by the excessive accumulation of fat in
adipose tissue and peripheral organs. Its derived metabolic complications are mediated by …