Freezing revisited: coordinated autonomic and central optimization of threat coping

K Roelofs, P Dayan - Nature Reviews Neuroscience, 2022 - nature.com
Animals have sophisticated mechanisms for coping with danger. Freezing is a unique state
that, upon threat detection, allows evidence to be gathered, response possibilities to be …

Principles of odor coding in vertebrates and artificial chemosensory systems

I Manzini, D Schild, C Di Natale - Physiological reviews, 2022 - journals.physiology.org
The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

[HTML][HTML] Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system

K Farsalinos, R Niaura, J Le Houezec, A Barbouni… - Toxicology reports, 2020 - Elsevier
As of 20 April, almost 1.7 million people globally have been diagnosed with Corona Virus
Disease 2019 (COVID-19), a pandemic that has evolved from the emergence of a new …

[HTML][HTML] The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases

NL Rey, DW Wesson, P Brundin - Neurobiology of disease, 2018 - Elsevier
Olfactory deficits are present in numerous neurodegenerative disorders and are
accompanied by pathology in related brain regions. In several of these disorders, olfactory …

Recent advances in the pathology of prodromal non-motor symptoms olfactory deficit and depression in Parkinson's disease: clues to early diagnosis and effective …

Y Bang, J Lim, HJ Choi - Archives of pharmacal research, 2021 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
movement dysfunction due to selective degeneration of dopaminergic neurons in the …

Cholinergic nervous system and glaucoma: From basic science to clinical applications

MA Faiq, G Wollstein, JS Schuman, KC Chan - Progress in retinal and eye …, 2019 - Elsevier
The cholinergic system has a crucial role to play in visual function. Although cholinergic
drugs have been a focus of attention as glaucoma medications for reducing eye pressure …

Extrinsic neuromodulation in the rodent olfactory bulb

D Brunert, M Rothermel - Cell and Tissue Research, 2021 - Springer
Evolutionarily, olfaction is one of the oldest senses and pivotal for an individual's health and
survival. The olfactory bulb (OB), as the first olfactory relay station in the brain, is known to …

Neuromodulation of olfactory transformations

C Linster, TA Cleland - Current opinion in neurobiology, 2016 - Elsevier
Highlights•Neuromodulators are widely represented throughout olfactory networks.•
Neuromodulators have diverse actions on cortical circuits.•Olfactory computations are …

Molecular imaging of the cholinergic system in Parkinson's disease

NI Bohnen, P Kanel, MLTM Müller - International review of neurobiology, 2018 - Elsevier
One of the first identified neurotransmitters in the brain, acetylcholine, is an important
modulator that drives changes in neuronal and glial activity. For more than two decades, the …

Differential muscarinic modulation in the olfactory bulb

RS Smith, R Hu, A DeSouza, CL Eberly… - Journal of …, 2015 - Soc Neuroscience
Neuromodulation of olfactory circuits by acetylcholine (ACh) plays an important role in odor
discrimination and learning. Early processing of chemosensory signals occurs in two …