3D cell culture systems: tumor application, advantages, and disadvantages

O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …

Advances in 3D cell culture technologies enabling tissue‐like structures to be created in vitro

E Knight, S Przyborski - Journal of anatomy, 2015 - Wiley Online Library
Research in mammalian cell biology often relies on developing in vitro models to enable the
growth of cells in the laboratory to investigate a specific biological mechanism or process …

Drug delivery and drug targeting with parenteral lipid nanoemulsions—A review

K Hörmann, A Zimmer - Journal of controlled release, 2016 - Elsevier
Lipid nanosized emulsions or nanoemulsions (NE) are oil in water dispersions with an oil
droplet size of about 200 nm. This size of oil droplets dispersed in a continuous water phase …

[HTML][HTML] Relationship and improvement strategies between drug nanocarrier characteristics and hemocompatibility: What can we learn from the literature

S Guo, Y Shi, Y Liang, L Liu, K Sun, Y Li - Asian Journal of Pharmaceutical …, 2021 - Elsevier
This article discusses the various blood interactions that may occur with various types of
nano drug-loading systems. Nanoparticles enter the blood circulation as foreign objects. On …

Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: a pilot study on rats

JB Đoković, SM Savić, JR Mitrović, I Nikolic… - International journal of …, 2021 - mdpi.com
The current study describes the experimental design guided development of PEGylated
nanoemulsions as parenteral delivery systems for curcumin, a powerful antioxidant, as well …

Improving glioblastoma therapeutic outcomes via doxorubicin-loaded nanomicelles modified with borneol

L Meng, X Chu, H Xing, X Liu, X Xin, L Chen… - International journal of …, 2019 - Elsevier
Glioblastoma is a grade IV malignant glioma with high recurrence and metastasis and faces
a therapeutic obstacle that the blood-brain barrier (BBB) severely hinders the brain entry …

Charge reversal self-emulsifying drug delivery systems: A comparative study among various phosphorylated surfactants

ZB Akkuş-Dağdeviren, JD Wolf, M Kurpiers… - Journal of Colloid and …, 2021 - Elsevier
Hypothesis Phosphorylated surfactants having ethoxylate spacer arms are promising
excipients for charge reversal self-emulsifying drug delivery systems (SEDDS). Experiments …

Biomacromolecule-based nanocarrier strategies to deliver plant-derived bioactive components for cancer treatment: A recent review

B Gorain, V Karmakar, B Sarkar, M Dwivedi… - International Journal of …, 2023 - Elsevier
The quest for safe chemotherapy has attracted researchers to explore anticancer potential of
herbal medicines. Owing to upsurging evidence of herbal drug's beneficial effects, hopes …

Palm oil in lipid-based formulations and drug delivery systems

D Efendy Goon, SH Sheikh Abdul Kadir, NA Latip… - Biomolecules, 2019 - mdpi.com
Palm oil is natural oil packed with important compounds and fatty acids ready to be exploited
in lipid-based formulations and drug delivery. Palm oil and palm kernel oil contain long …

Development and in vitro evaluation of vitamin E-enriched nanoemulsion vehicles loaded with genistein for chemoprevention against UVB-induced skin damage

B Brownlow, VJ Nagaraj, A Nayel, M Joshi… - Journal of …, 2015 - Elsevier
There is a great need for effective protection against cutaneous pathologies arising from
chronic exposure to harmful solar UVB radiations. A promising pharmaceutical strategy to …