IL-37 was discovered as an anti-inflammatory and immunosuppressive cytokine of the IL-1
family. Significant advancements in the understanding of signaling pathways associated …

Autoimmune diseases (AIDs) are characterized by dysfunction and tissue destruction, and
recent studies have shown that interleukin (IL)‑37 expression is dysregulated in AIDs …

A global pandemic has erupted as a result of the new brand coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …

Our study aims to verify the potential effects and underlying mechanisms of IL-37 in
Coxsackievirus B3 (CVB3)-induced viral myocarditis (VMC). VMC model was established by …

Ankylosing spondylitis (AS) is an immune-mediated inflammatory disorder that primarily
affects the axial skeleton, especially the sacroiliac joints and spine. This results in chronic …

Ankylosing spondylitis (AS) is a seronegative, chronic inflammatory arthritis with high
genetic burden. A strong association with HLA-B27 has long been established, but to date …

Background A previous study indicated that gut microbiota changed notably in Graves'
orbitopathy (GO) patients as compared to controls. However, the characteristics of intestinal …

Interleukin-38 (IL-38), a new cytokine of interleukin-1 family (IL-1F), is expressed in the
human heart, kidney, skin, etc. Recently, new evidence indicated that IL-38 is involved in the …

Objective Our study was designed to explore the role of IL‐37 in M1/M2 macrophage
polarization imbalance in the pathogenesis of periodontitis. Background Periodontitis is a …

Objective Periodontitis is an inflammatory disease, characterized by periodontal pocket
formation and alveolar bone resorption, is one of the most common oral diseases …