BACKGROUND Chemotherapy-associated ovarian damage (CAOD) is one of the most
feared short-and long-term side effects of anticancer treatment in premenopausal women …

Premature ovarian failure (POF) is a common female reproductive disorder and
characterized by menopause, increased gonadotropin levels and estrogen deficiency before …

The ovary ages earlier than most other tissues, yet the underlying mechanisms remain
elusive. Here a comprehensive analysis of transcriptomic landscapes in different organs in …

Background Primary ovarian insufficiency (POI) is a common gynecological disease with
serious ramifications including low pregnancy rate and low estrogen symptoms. Traditional …

Purpose of review To describe the immunological mechanism in the pathogenesis of
premature ovarian insufficiency (POI), summarize the alternations in humoral immunity and …

The ovary is a female reproductive organ that plays a key role in fertility and the
maintenance of endocrine homeostasis, which is of great importance to women's health. It is …

The systematic toxicological mechanism of cigarette smoke (CS) on ovarian reserve has not
been extensively investigated. Female 8-week-old C57BL/6 mice at peak fertility were …

Premature ovarian failure (POF) caused by chemotherapy is a growing concern for female
reproductive health. The use of metformin (MET), which has anti-oxidative and anti …

Background Premature ovarian insufficiency (POI) is an important cause of infertility
characterized by the functional decline of the ovary. Granulosa cells (GCs) around oocytes …

Ovarian aging is characterized by a progressive decline in ovarian function. With the
increase in life expectancy worldwide, ovarian aging has gradually become a key health …