The complex network of malfunctioning pathways occurring in the pathogenesis of
neurodegenerative diseases (NDDs) represents a huge hurdle in the development of new …

The effects of Copper oxide nanoparticles (CuO-NPs) have been investigated on human
cells and various experimental animals. However, there is a lack of research on the effects of …

Bisphenol A (BPA) is a widespread compound associated with the manufacture of many
consumer products. The BPA-induced reproductive toxicity was reported to be mainly …

Abstract Copper oxide nanoparticles (CuO-NPs) are consciously used to control the growth
of bacteria, fungi, and algae. Several studies documented the beneficial and hazardous …

Hepatic injury is a major side effect associated with methotrexate (MTX) therapy resulting
from inflammatory reactions and oxidative stress induction. Therefore, liver fibrosis incidence …

Despite all the studies performed to date, therapy choices for liver injuries are very few.
Therefore, the search for a new treatment that could safely and effectively block or reverse …

The clinical application of cyclosporine A (CsA) as an immunosuppressive agent is limited
by its organ toxicity. We aimed to evaluate the effectiveness of α-lipoic acid against CsA …

There is increasing scientific evidences that the physical and chemical properties of
manufactured nanoparticles lead to an increase in their bioavailability and toxicity. Among …

This study examined if regulating the keap-1? Nrf2 antioxidant pathway mediated gold
nanoparticles (AuNPs) induced liver damage, and examined the protective effect of co …

The current study aimed to evaluate the harmful effect of chlorpyrifos (CPF) on the
reproductive functions and fertility in male rats and to assess the protective role of zinc (Zn) …