Metastasis, a critical phase of tumor progression, remains a primary challenge in treating
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …

'Inflammaging'refers to the chronic, low-grade inflammation that characterizes aging.
Inflammaging is macrophage centered, involves several tissues and organs, including the …

Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …

Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …

Cellular senescence is a state of terminal growth arrest associated with the upregulation of
different cell cycle inhibitors, mainly p16 and p21, structural and metabolic alterations …

Cellular senescence occurs in proliferating cells as a consequence of various triggers
including telomere shortening, DNA damage, and inappropriate expression of oncogenes …

Exosomes are a class of extracellular vesicles ranging in size from 40 to 100 nm, which are
secreted by both cancer cells and multiple stromal cells in the tumor microenvironment …

Aging is consistently reported as the most important independent risk factor for
neurodegenerative diseases. As life expectancy has significantly increased during the last …

Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

Ovarian cancer is the most lethal malignancy among the gynecological cancers, with a 5‐
year survival rate, mainly due to being diagnosed at advanced stages, recurrence and …