Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

Sickle cell disease (SCD) is the most common inherited blood disorder in the United States,
and a global health problem. Pathological features of the abnormal hemoglobin (HbS) result …

It is well-established that patients with sickle cell disease (SCD) are at substantial risk of
neurological complications, including overt and silent stroke, microstructural injury, and …

With increasing survival, cumulative complications of sickle cell disease (SCD), which
develop insidiously over time, are becoming more apparent and common in older patients …

In this first population-based study of moyamoya disease (MMD) in Europe, the authors
identified 56 patients with MMD in Denmark during the period 1994–2015 using nationwide …

Introduction: Over the past decades, neuroimaging studies have clarified that a significant
proportion of patients with sickle cell disease (SCD) have functionally significant brain …

Sickle cell disease is the most common hereditary hemoglobinopathy, which results in
abnormally shaped and rigid red blood cells. These sickle‐shaped red blood cells cause …

Although hemodynamic stress plays a key role in aneurysm formation outside of sickle cell
disease (SCD), its role is understudied in patients with SCD. We hypothesized that tissue …

Sickle cell disease (SCD) is caused by the presence of hemoglobin S (HbS, a2b2 S). The
syndrome comprises different genotypes that include homozygous S (HbSS): compound …

In countries with access to organized health care, survival of children with sickle cell disease
(SCD) has greatly improved, resulting in a growing population of adults with SCD. Transition …