The programmed cell death 10 (PDCD10) gene was originally identified as an apoptosis-
related gene, although it is now usually known as CCM3, as the third causative gene of …

Cerebral cavernous malformation (CCM) is a neurovascular familial or sporadic disease that
is characterised by capillary-venous cavernomas, and is due to loss-of-function mutations to …

Simple Summary As an adaptor protein, PDCD10 is involved in regulation of diverse
biological processes by interacting with multiple molecules. Recently, growing amounts of …

MicroRNA (miR)-26a-5p and miR-26b-5p consistently play an antitumor role in many types
of cancers, but the underlying mechanism remains unclear in bladder cancer (BC). In the …

Purpose Oxaliplatin (OX) is widely used for patients with advanced colorectal cancer (CRC).
However, most of them will turn out to be OX resistant. Therefore, it is necessary to uncover …

Background Osteosarcoma, a common primary malignant tumor, occurs in children and
adolescents with a poor prognosis. The current treatment methods are various, while the five …

Metallothionein-3 has poorly characterized functions in neuroblastoma. Cisplatin-based
chemotherapy is a major regimen to treat neuroblastoma, but its clinical efficacy is limited by …

Cerebral cavernous malformations (CCMs) are microvascular anomalies in the brain that
result in increased susceptibility to stroke. Three genes have been identified as causes of …

The atypical cadherin FAT1 function either as a pro or antitumorigenic in tumors of different
tissue origins. Our group previously demonstrated the protumorigenic nature of FAT1 …

Background ALDH1A3 is a cancer stem cell marker in neoplasms including glioblastoma
(GBM). However, the comprehensive role of ALDH1A3 in GBM remains unclear. This study …