RNA G-quadruplexes (rG4s): genomics and biological functions
Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …
have been first observed decades ago. Over the years, these four-stranded structural motifs …
A guide to computational methods for G-quadruplex prediction
E Puig Lombardi, A Londoño-Vallejo - Nucleic acids research, 2020 - academic.oup.com
Guanine-rich nucleic acids can fold into the non-B DNA or RNA structures called G-
quadruplexes (G4). Recent methodological developments have allowed the characterization …
quadruplexes (G4). Recent methodological developments have allowed the characterization …
[HTML][HTML] Multiscale analysis of independent Alzheimer's cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus
Investigators have long suspected that pathogenic microbes might contribute to the onset
and progression of Alzheimer's disease (AD) although definitive evidence has not been …
and progression of Alzheimer's disease (AD) although definitive evidence has not been …
RNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria
INTRODUCTION Many cellular RNAs contain regions that fold into stable structures required
for function. Both Watson− Crick and noncanonical interactions can play important roles in …
for function. Both Watson− Crick and noncanonical interactions can play important roles in …
RNA G-quadruplexes: emerging mechanisms in disease
A Cammas, S Millevoi - Nucleic acids research, 2017 - academic.oup.com
Abstract RNA G-quadruplexes (G4s) are formed by G-rich RNA sequences in protein-coding
(mRNA) and non-coding (ncRNA) transcripts that fold into a four-stranded conformation …
(mRNA) and non-coding (ncRNA) transcripts that fold into a four-stranded conformation …
The diverse structural landscape of quadruplexes
G‐quadruplexes are secondary structures formed in G‐rich sequences in DNA and RNA.
Considerable research over the past three decades has led to in‐depth insight into these …
Considerable research over the past three decades has led to in‐depth insight into these …
rG4detector, a novel RNA G-quadruplex predictor, uncovers their impact on stress granule formation
M Turner, YM Danino, M Barshai… - Nucleic acids …, 2022 - academic.oup.com
RNA G-quadruplexes (rG4s) are RNA secondary structures, which are formed by guanine-
rich sequences and have important cellular functions. Existing computational tools for rG4 …
rich sequences and have important cellular functions. Existing computational tools for rG4 …
QUADRatlas: the RNA G-quadruplex and RG4-binding proteins database
S Bourdon, P Herviou, L Dumas… - Nucleic Acids …, 2023 - academic.oup.com
Abstract RNA G-quadruplexes (RG4s) are non-canonical, disease-associated post-
transcriptional regulators of gene expression whose functions are driven by RNA-binding …
transcriptional regulators of gene expression whose functions are driven by RNA-binding …
Non-duplex G-quadruplex structures emerge as mediators of epigenetic modifications
The role of non-duplex DNA, the guanine-quadruplex structure in particular, is becoming
widely appreciated. Increasing evidence in the last decade implicates quadruplexes in …
widely appreciated. Increasing evidence in the last decade implicates quadruplexes in …
Motif independent identification of potential RNA G-quadruplexes by G4RNA screener
Motivation G-quadruplex structures in RNA molecules are known to have regulatory impacts
in cells but are difficult to locate in the genome. The minimal requirements for G-quadruplex …
in cells but are difficult to locate in the genome. The minimal requirements for G-quadruplex …