Cytochromes P450 (P450) are hemoproteins encoded by a superfamily of genes nearly
ubiquitously distributed in different organisms from all biological kingdoms. The reactions …

Metabolism is a highly interconnected web of chemical reactions that power life. Though the
stoichiometry of metabolism is well understood, the multidimensional aspects of metabolic …

We have witnessed a dramatic increase in the frequency and diversity of herbicide-resistant
weed biotypes over the past two decades, which poses a threat to the sustainability of …

Cytochromes P450 catalyse extremely diverse and often complex regiospecific and/or
stereospecific reactions in the biosynthesis or catabolism of plant bioactive molecules …

Although over 80 cytochrome P450 (CYP) encoding genes have been identified in the
genome of the nematode Caenorhabditis elegans very little is known about their …

We identified 672, 374, and 379 CYPs proteins encoded by the CYPs genes in Gossypium
hirsutum, Gossypium raimondii, and Gossypium arboreum, respectively. The genes were …

The high plasticity of the active-site cavity of cytochromes P450, permitting reactivity toward
a vast array of compounds, makes these enzymes attractive targets for biotechnological …

Transgenic potato and rice plants were generated by the introduction of human P450
species, CYP1A1, CYP2B6, CYP2C9 and CYP2C19, which metabolized a number of …

Cytochrome P450 monooxygenases (P450s) metabolize herbicides to produce mainly non-
phytotoxic metabolites. Although rice plants endogenously express multiple P450 enzymes …

Metabolism of 50 herbicides and 7 other chemicals with different structures and modes of
action was examined in the microsomes from the recombinant yeast strains expressing each …