Mitochondria have cell-type specific phenotypes, perform dozens of interconnected
functions and undergo dynamic and often reversible physiological recalibrations. Given their …

Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …

Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Mitochondrial-derived vesicles (MDVs) are implicated in diverse physiological processes—
for example, mitochondrial quality control—and are linked to various neurodegenerative …

Recent findings have demonstrated that mitochondria can be transferred between cells to
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …

Aging is a complex process that features a functional decline in many organelles. Although
mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of …

Mitochondria are central hubs of cellular metabolism that also play key roles in signaling
and disease. It is therefore fundamentally important that mitochondrial quality and activity …

Mitochondria are essential organelles that execute and coordinate various metabolic
processes in the cell. Mitochondrial dysfunction severely affects cell fitness and contributes …

That certain cell types in the central nervous system are more likely to undergo
neurodegeneration in Parkinson's disease is a widely appreciated but poorly understood …

Mitochondria are central hubs of cellular metabolism and are tightly connected to signaling
pathways. The dynamic plasticity of mitochondria to fuse, divide, and contact other …