Poly (beta-amino alcohols), their preparation, and uses thereof
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vitro. Furthermore, these coatings reduce the recruitment of inflammatory cells, and reduce …
vitro. Furthermore, these coatings reduce the recruitment of inflammatory cells, and reduce …
Biodegradable poly (beta-amino esters) and uses thereof
The safe and efficient delivery of therapeutic DNA to cells represents a fundamental obstacle
to the clinical Success of gene therapy (Luo et al. Nat. Biotechnol. 18: 33-37, 2000; …
to the clinical Success of gene therapy (Luo et al. Nat. Biotechnol. 18: 33-37, 2000; …
Biodegradable poly (beta-amino esters) and uses thereof
(57) ABSTRACT Poly (3-amino esters) prepared from the conjugate addition of bis
(secondary amines) or primary amines to a bis (acrylate ester) are described. Methods of …
(secondary amines) or primary amines to a bis (acrylate ester) are described. Methods of …
Crosslinked, degradable polymers and uses thereof
Acrylate-terminated poly (beta-amino esters) are cross-linked to form materials useful in the
medical as well as non-medical field. The polymeric starting material is combined with a free …
medical as well as non-medical field. The polymeric starting material is combined with a free …
Aptamer regulated nucleic acids and uses thereof
US9315862B2 - Aptamer regulated nucleic acids and uses thereof - Google Patents
US9315862B2 - Aptamer regulated nucleic acids and uses thereof - Google Patents Aptamer …
US9315862B2 - Aptamer regulated nucleic acids and uses thereof - Google Patents Aptamer …
Biodegradable poly (β-amino esters) and uses thereof
2010-08-31 Assigned to MASSACHUSETTS INSTITUTE OF TECHNOLOGY reassignment
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …
Biodegradable poly (beta-amino esters) and uses thereof
The safe and efficient delivery of therapeutic DNA to cells represents a fundamental obstacle
to the clinical Success of gene therapy (Luo et al. Nat. Biotechnol. 18: 33-37, 2000; …
to the clinical Success of gene therapy (Luo et al. Nat. Biotechnol. 18: 33-37, 2000; …
Conjugates containing hydrophilic spacer linkers
CP Leamon, IR Vlahov, HKR Santhapuram… - US Patent …, 2015 - Google Patents
Described herein are compositions and methods for use in targeted drug delivery using cell
receptor binding drug deliv ery conjugates containing hydrophilic spacer linkers for use in …
receptor binding drug deliv ery conjugates containing hydrophilic spacer linkers for use in …
Signal activated RNA interference
SP Han, RD Barish, WA Goddard III - US Patent 9,029,524, 2015 - Google Patents
2009-07-15 Assigned to CALIFORNIA INSTITUTE OF TECHNOLOGY reassignment
CALIFORNIA INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS INTEREST …
CALIFORNIA INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS INTEREST …
Psma binding ligand-linker conjugates and methods for using
PS Low, SA Kularatne - US Patent 9,193,763, 2015 - Google Patents
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5,863,536 A 1/1999 Jackson et al. 5,902,817 A 5, 1999 Jackson et al. 5,962,521 A 10, 1999 …