Distinct patterns of disease activity over time in patients with active SLE revealed using latent class trajectory models

JA Reynolds, J Prattley, N Geifman, M Lunt… - Arthritis research & …, 2021 - Springer
Background Systemic lupus erythematosus (SLE) is a heterogeneous systemic autoimmune
condition for which there are limited licensed therapies. Clinical trial design is challenging in …

Improved Prediction of Perimetric Loss in Glaucomatous Eyes Using Latent Class Mixed Modeling

SS Swaminathan, AA Jammal, JS Rao… - Ophthalmology …, 2023 - Elsevier
Purpose To evaluate whether the identification of distinct classes within a population of
glaucoma patients improves estimates of future perimetric loss. Design Longitudinal cohort …

A Multi-Omic Approach to Stratified Medicine in Rheumatoid Arthritis

K Goldmann - 2022 - qmro.qmul.ac.uk
Rheumatoid arthritis (RA) is a chronic, systemic, and progressive autoimmune disease
primarily affecting synovial joints. It is characterised by immune cell-infiltration, severe …

Do traditional BMI categories capture future obesity? A comparison with trajectories of BMI and incidence of cancer

C Watson, N Geifman - AMIA Annual Symposium Proceedings, 2021 - pmc.ncbi.nlm.nih.gov
In 2016, 13 specific obesity related cancers were identified by IARC. Here, using baseline
WHO BMI categories, latent profile analysis (LPA) and latent class trajectory modelling …