Early disease biomarkers can be found using animal models urine proteomics

J Wei, Y Gao - Expert Review of Proteomics, 2021 - Taylor & Francis
Introduction Early disease detection is a prerequisite for early intervention. Urine is not
subjected to homeostatic control, and therefore, it accumulates very early changes …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Genomics, microRNA, epigenetics, and proteomics for future diagnosis, treatment and monitoring response in upper GI cancers

BLDM Brücher, Y Li, P Schnabel, M Daumer… - Clinical and …, 2016 - Springer
One major objective for our evolving understanding in the treatment of cancers will be to
address how a combination of diagnosis and treatment strategies can be used to integrate …

Insight into the molecular basis of Schistosoma haematobium-induced bladder cancer through urine proteomics

C Bernardo, MC Cunha, JH Santos, JMC da Costa… - Tumor Biology, 2016 - Springer
Infection due to Schistosoma haematobium is carcinogenic. However, the cellular and
molecular mechanisms underlying urogenital schistosomiasis (UGS)-induced …

Urine proteome changes in rats subcutaneously inoculated with approximately ten tumor cells

J Wei, W Meng, Y Gao - PeerJ, 2019 - peerj.com
Background Biomarkers are changes associated with the disease. Urine is not subject to
homeostatic control and therefore accumulates very early changes, making it an ideal …

Fe-doped chrysotile nanotubes containing siRNAs to silence SPAG5 to treat bladder cancer

J Liu, Y Zhang, H Zeng, L Wang, Q Zhang, P Wu… - Journal of …, 2021 - Springer
Background For certain human cancers, sperm associated antigen 5 (SPAG5) exerts
important functions for their development and progression. However, whether RNA …

Quantitative proteomic analysis of a genetically induced prostate inflammation mouse model via custom 4-plex DiLeu isobaric labeling

L Hao, S Thomas, T Greer, CM Vezina… - American Journal …, 2019 - journals.physiology.org
Inflammation is involved in many prostate pathologies including infection, benign prostatic
hyperplasia, and prostate cancer. Preclinical models are critical to our understanding of …

Microbiome and morbid obesity increase pathogenic stimulus diversity

BLDM Brücher, IS Jamall - 4open, 2019 - 4open-sciences.org
The microbiome, the relationship between environmental factors, a high-fat diet, morbid
obesity, and host response have been associated with cancer, only a small fraction of which …

Tracking Prostate Carcinogenesis over Time through Urine Proteome Profiling in an Animal Model: An Exploratory Approach

A Moreira-Pais, R Nogueira-Ferreira, S Reis… - International Journal of …, 2022 - mdpi.com
Prostate cancer (PCa) is one of the most lethal diseases in men, which justifies the search
for new diagnostic tools. The aim of the present study was to gain new insights into the …

[PDF][PDF] Простатический специфический антиген в моче и крови у мужчин и женщин

ДЮ Соснин, КР Галькович, ВА Легостина… - Клиническая …, 2023 - clinlabdia.ru
Рост онкологических заболеваний обусловливает интерес к исследованию динамики
онкомаркеров не только в сыворотке крови, но и в других биологических жидкостях …