miRNAs in the Diagnosis and Prognosis of Skin Cancer

M Neagu, C Constantin, SM Cretoiu… - Frontiers in cell and …, 2020 - frontiersin.org
Skin cancer is, at present, the most common type of malignancy in the Caucasian
population. Its incidence has increased rapidly in the last decade for both melanoma and …

Role of microRNAs as clinical cancer biomarkers for ovarian cancer: a short overview

CE Staicu, DV Predescu, CM Rusu, BM Radu… - Cells, 2020 - mdpi.com
Ovarian cancer has the highest mortality rate among gynecological cancers. Early clinical
signs are missing and there is an urgent need to establish early diagnosis biomarkers …

Foetoplacental communication via extracellular vesicles in normal pregnancy and preeclampsia

DI Chiarello, R Salsoso, F Toledo, A Mate… - Molecular aspects of …, 2018 - Elsevier
Intercellular communication is a critical process in biological mechanisms. During
pregnancy foetoplacental tissues release a heterogeneous group of extracellular vesicles …

Circulating miRNAs and preeclampsia: from implantation to epigenetics

SR Giannubilo, M Cecati, D Marzioni… - International Journal of …, 2024 - mdpi.com
In this review, we comprehensively present the literature on circulating microRNAs
(miRNAs) associated with preeclampsia, a pregnancy-specific disease considered the …

Roles of microRNA across prenatal and postnatal periods

I Floris, JD Kraft, I Altosaar - International journal of molecular sciences, 2016 - mdpi.com
Communication between mother and offspring in mammals starts at implantation via the
maternal–placental–fetal axis, and continues postpartum via milk targeted to the intestinal …

The role of cluster C19MC in pre-eclampsia development

I Jaszczuk, I Winkler, D Koczkodaj… - International Journal of …, 2022 - mdpi.com
Pre-eclampsia is a placenta-related complication occurring in 2–10% of all pregnancies.
miRNAs are a group of non-coding RNAs regulating gene expression. There is evidence …

Diagnostic potential of microRNAs as biomarkers in the detection of preeclampsia

A Hornakova, Z Kolkova, V Holubekova… - Genetic Testing and …, 2020 - liebertpub.com
Preeclampsia is a multisystemic disorder that occurs in 5–8% of pregnant women and
remains a leading cause of both maternal and fetal morbidity and mortality. The disease is …

Deregulation of miR-324/KISS1/kisspeptin in early ectopic pregnancy: mechanistic findings with clinical and diagnostic implications

A Romero-Ruiz, MS Avendaño, F Dominguez… - American journal of …, 2019 - Elsevier
Background Ectopic pregnancy is a life-threatening condition for which novel screening
tools that would enable early accurate diagnosis would improve clinical outcomes …

Improving the diagnostic potential of extracellular miRNAs coupled to multiomics data by exploiting the power of artificial intelligence

A Paolini, A Baldassarre, SP Bruno, C Felli… - Frontiers in …, 2022 - frontiersin.org
In recent years, the clinical use of extracellular miRNAs as potential biomarkers of disease
has increasingly emerged as a new and powerful tool. Serum, urine, saliva and stool contain …

Serum miR-125b levels associated with epithelial ovarian cancer (EOC) development and treatment responses

Z Chen, X Guo, S Sun, C Lu, L Wang - Bioengineered, 2020 - Taylor & Francis
Downexpression of miRs was associated with tumor development, progression, and
metastasis. This study explored the serum levels of miR-125b in patients with epithelial …