Excessive cellular growth is a major contributor to pathological changes associated with
diabetic nephropathy. In particular, high glucose-induced growth of glomerular mesangial …

Diabetes-related complications are a significant source of morbidity and mortality worldwide.
Diabetic kidney disease is a frequent microvascular complication and a primary cause of …

Most of the late diabetic complications such as retinopathy, nephropathy, and neuropathy,
have their basis in disturbed microvascular function. Structural and functional changes in the …

This review is about vascular endothelial phenotype heterogeneity in the retinal and
choroidal circulations. It is becoming increasingly clear that the functional and structural …

The endothelin (ET) system consists of three peptide ligands (ET-1, ET-2 and ET-3) and two
G-protein-coupled receptors, ETA and ETB. In the cardiovascular system, ETs, particularly …

The requirements of metabolizing tissue are both continuous and variable; accordingly, the
microvasculature serving that tissue must be similarly dynamic. Just as it is recognized that …

OBJECTIVE To establish a method for isolation and culture of subcutaneous microvascular
endothelial cells (MVEC) from small human tissue biopsies to compare gene and protein …

An explosion in global epidemic of type 2 diabetes mellitus poses major rise in cases with
vascular endothelial dysfunction ranging from micro-(retinopathy, nephropathy and …

Background: Exposures to ambient air pollution during pregnancy have been linked to
adverse pregnancy outcomes such as preeclampsia and fetal growth restriction. Although …

Coronary microvascular dysfunction (CMD) has been proposed as an important component
of diabetes mellitus (DM)-and hypercholesterolemia-associated coronary artery disease …