Simple Summary Cancer cells alter their metabolisms to support growth, thus causing micro-
and macronutrient changes in the metabolite profile that promote an immunosuppressive …

Breast cancer (BC) represents the most prevalent cancer in women at any age after puberty.
From a pathogenetic prospective, despite a wide array of risk factors being identified thus …

The existence of a tight relationship between inflammation and epigenetics that in primary
breast tumor cells can lead to tumor progression and the formation of bone metastases was …

Purpose Breast cancer (BC) is the most common malignancy that affects women, and it is, to
date, their leading cause of death. Luminal A molecular subtype accounts for 40% of BC and …

Breast cancer has been reported to transcend lung cancer as the most commonly diagnosed
cancer in women all over the world. Adipocytes, serving as energy storage and endocrine …

Background Matricellular proteins comprising matrisome and adhesome are responsible for
structure integrity and interactions between cells in the tumour microenvironment of breast …

Obesity, the global pandemic since industrialization, is the number one lifestyle-related risk
factor for premature death, which increases the incidence and mortality of various diseases …

Triple‐negative breast cancer (TNBC) is a highly aggressive and metastatic malignancy with
poor treatment outcomes. The interaction between the tumor microenvironment (TME) and …

Obesity exacerbates the risk and aggressiveness of many types of cancer. Adipose tissue
(AT) represents a prevalent component of the tumor microenvironment (TME) and …

Breast cancer is the most prevalent cancer in women worldwide. Whilst overall breast
cancer (BC) survival rates have improved, metastatic breast cancers remain fatal. Metastatic …