From co-infections to autoimmune disease via hyperactivated innate immunity: COVID-19 autoimmune coagulopathies, autoimmune myocarditis and multisystem …

R Root-Bernstein - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophilia and the production of neutrophil extracellular traps (NETs) are two of many
measures of increased inflammation in severe COVID-19 that also accompany its …

The role of monocytes in thrombotic diseases: a review

Z Han, Q Liu, H Li, M Zhang, L You, Y Lin… - Frontiers in …, 2023 - frontiersin.org
Cardiovascular and cerebrovascular diseases are the number one killer threatening
people's life and health, among which cardiovascular thrombotic events are the most …

The role of neutrophil extracellular traps (NETs) in the pathogenesis of systemic lupus erythematosus and antiphospholipid syndrome

T Reshetnyak, K Nurbaeva - International Journal of Molecular Sciences, 2023 - mdpi.com
Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are two related
autoimmune diseases. In recent years, there has been sufficient evidence to suggest that …

Thrombocytopenia in antiphospholipid syndrome: is anticoagulation and/or antiaggregation always required?

S Zuily, R Cervera, T Foret, S Bertocchi, A Tincani - Autoimmunity Reviews, 2024 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune and prothrombotic condition
defined by the association of thrombotic events and/or obstetrical complications and the …

An update on inflammation in antiphospholipid syndrome

A Ambati, Y Zuo, JS Knight - Current opinion in rheumatology, 2023 - journals.lww.com
An update on inflammation in antiphospholipid syndrome : Current Opinion in Rheumatology An
update on inflammation in antiphospholipid syndrome : Current Opinion in Rheumatology Log in …

Differences in antiphospholipid antibody profile between patients with obstetric and thrombotic antiphospholipid syndrome

A Anunciación-Llunell, C Muñoz… - International journal of …, 2022 - mdpi.com
Antiphospholipid syndrome (APS) is a systemic autoimmune condition characterised by the
presence of antiphospholipid antibodies (aPL) associated with vascular thrombosis and/or …

Antiphospholipid antibody carriers and patients with quiescent antiphospholipid syndrome show persistent subclinical complement activation

M Zen, M Tonello, M Favaro, T Del Ross… - …, 2024 - academic.oup.com
Objectives Complement activation has been advocated as one mechanism by which aPLs
can induce thrombosis. In patients with catastrophic APS or re-thrombosis, enhanced …

ARID5B‐mediated LINC01128 epigenetically activated pyroptosis and apoptosis by promoting the formation of the BTF3/STAT3 complex in β2GPI/anti‐β2GPI‐treated …

Y Tan, J Qiao, S Yang, Q Wang, H Liu… - Clinical and …, 2024 - Wiley Online Library
Background Alterations of the trimethylation of histone 3 lysine 4 (H3K4me3) mark in
monocytes are implicated in the development of autoimmune diseases. Therefore, the …

Platelets and Thrombotic Antiphospholipid Syndrome

I Tohidi-Esfahani, P Mittal, D Isenberg… - Journal of Clinical …, 2024 - mdpi.com
Antiphospholipid antibody syndrome (APS) is an autoimmune disorder characterised by
thrombosis and the presence of antiphospholipid antibodies (aPL): lupus anticoagulant …

Can complement activation be the missing link in antiphospholipid syndrome?

V Venturelli, B Maranini, I Tohidi-Esfahani… - …, 2024 - academic.oup.com
APS is an autoimmune disorder with life-threatening complications that, despite therapeutic
advantages, remains associated with thrombotic recurrences and treatment failure. The role …