Spin hyperpolarization in modern magnetic resonance
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …
disciplines and in various practical applications, with medical magnetic resonance imaging …
MATRESHCA: Microtesla Apparatus for Transfer of Resonance Enhancement of Spin Hyperpolarization via Chemical Exchange and Addition
We present an integrated, open-source device for parahydrogen-based hyperpolarization
processes in the microtesla field regime with a cost of components of less than $7000. The …
processes in the microtesla field regime with a cost of components of less than $7000. The …
Low-cost high-pressure clinical-scale 50% parahydrogen generator using liquid nitrogen at 77 K
B Chapman, B Joalland, C Meersman… - Analytical …, 2021 - ACS Publications
We report on a robust and low-cost parahydrogen generator design employing liquid
nitrogen as a coolant. The core of the generator consists of catalyst-filled spiral copper …
nitrogen as a coolant. The core of the generator consists of catalyst-filled spiral copper …
Delivering Robust Proton-Only Sensing of Hyperpolarized [1,2-13C2]-Pyruvate Using Broad-Spectral-Range Nuclear Magnetic Resonance Pulse Sequences
I Mandzhieva, I Adelabu, S Nantogma… - ACS …, 2023 - ACS Publications
Hyperpolarized [1-13C] pyruvate is the leading hyperpolarized injectable contrast agent and
is currently under evaluation in clinical trials for molecular imaging of metabolic diseases …
is currently under evaluation in clinical trials for molecular imaging of metabolic diseases …
Proton-Only Sensing of Hyperpolarized [1,2-13C2]Pyruvate
Hyperpolarized MRI is emerging as a next-generation molecular imaging modality that can
detect metabolic transformations in real time deep inside tissue and organs. 13C …
detect metabolic transformations in real time deep inside tissue and organs. 13C …
Carbon-13 Radiofrequency Amplification by Stimulated Emission of Radiation of the Hyperpolarized Ketone and Hemiketal Forms of Allyl [1-13C]Pyruvate
13C hyperpolarized pyruvate is an emerging MRI contrast agent for sensing molecular
events in cancer and other diseases with aberrant metabolic pathways. This metabolic …
events in cancer and other diseases with aberrant metabolic pathways. This metabolic …
Efficient SABRE-SHEATH Hyperpolarization of Potent Branched-Chain-Amino-Acid Metabolic Probe [1-13C]ketoisocaproate
Efficient 13C hyperpolarization of ketoisocaproate is demonstrated in natural isotopic
abundance and [1-13C] enriched forms via SABRE-SHEATH (Signal Amplification By …
abundance and [1-13C] enriched forms via SABRE-SHEATH (Signal Amplification By …
Interplay of Near-Zero-Field Dephasing, Rephasing, and Relaxation Dynamics and [1-13C]Pyruvate Polarization Transfer Efficiency in Pulsed SABRE-SHEATH
Hyperpolarized [1-13C] pyruvate is a revolutionary molecular probe enabling ultrafast
metabolic MRI scans in 1 min. This technology is now under evaluation in over 30 clinical …
metabolic MRI scans in 1 min. This technology is now under evaluation in over 30 clinical …
Spin hyperpolarization in modern magnetic resonance
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in a number of practical applications, with medical MRI being the most …
disciplines and in a number of practical applications, with medical MRI being the most …
Scanning Nuclear Spin Level Anticrossings by Constant-Adiabaticity Magnetic Field Sweeping of Parahydrogen-Induced 13C Polarization
B Joalland, EY Chekmenev - The Journal of Physical Chemistry …, 2022 - ACS Publications
The polarization transfer between 1H protons and 13C heteronuclei is of central importance
in the development of parahydrogen-based hyperpolarization techniques dedicated to the …
in the development of parahydrogen-based hyperpolarization techniques dedicated to the …