Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players

NI Rizk, AI Abulsoud, MM Kamal, DH Kassem… - Life sciences, 2022 - Elsevier
Exosomes are nano-vesicles (NVs) secreted by cells and take part in cell-cell
communications. Lately, these exosomes were proved to have dual faces in cancer …

[HTML][HTML] Using intervention mapping to develop a theory-based intervention to promote colorectal cancer screening in Egypt

A Nawwar, LB Bateman, S Khamess… - Asian Pacific Journal …, 2022 - ncbi.nlm.nih.gov
Background: Colorectal cancer (CRC) incidence and mortality rates are increasing in Egypt.
Because no national screening guidelines exist, developing an effective evidence-based …

Microbiome diversity in African American, European American, and Egyptian colorectal cancer patients

A Elkholy, N Avuthu, M Abdalla, M Behring, P Bajpai… - Heliyon, 2023 - cell.com
Purpose Although there is an established role for microbiome dysbiosis in the pathobiology
of colorectal cancer (CRC), CRC patients of various race/ethnicities demonstrate distinct …

[HTML][HTML] Reposition of the anti-inflammatory drug diacerein in an in-vivo colorectal cancer model

RT Abdel-Latif, W Wadie, Y Abdel-Mottaleb… - Saudi Pharmaceutical …, 2022 - Elsevier
Abstract Excessive interleukin (IL)-6 production is a driver for malignancy and drug
resistance in colorectal cancer (CRC). Our study investigated a seven-week post-treatment …

Designing an effective colorectal cancer screening program in Egypt: a qualitative study of perceptions of Egyptian primary care physicians and specialists

L Brand Bateman, S Khamess, SE Abdelmoneim… - The …, 2020 - academic.oup.com
Abstract Background In Egypt more than one‐third of colorectal cancer (CRC) cases occur in
individuals aged 40 years and younger, and are diagnosed at advanced stages; currently …

Role of extracellular LncRNA-SNHG14/miRNA-3940-5p/NAP12 mRNA in colorectal cancer

M Matboli, AE Shafei, MA Ali… - … of physiology and …, 2021 - Taylor & Francis
Background We aim to identify and analyze the expression of dyregulated RNAs in
colorectal cancer (CRC). Methods We selected a panel of RNAs specific to CRC composed …

[HTML][HTML] Association of lncRNA MEG3 Rs7158663 polymorphism and serum expression with colorectal cancer in Egyptian Patients

ME Elsherbeny, AR Elsergany… - Reports of Biochemistry & …, 2023 - ncbi.nlm.nih.gov
Background: Colorectal cancer (CRC) is considered the third most common cancer around
the world and second in terms of mortality. A significant aspect in its development is …

Prognostic value of TWIST1 and EZH2 expression in colon cancer

SM Abdel Raouf, TR Ibrahim, LA Abdelaziz… - Journal of …, 2021 - Springer
Background Colorectal carcinoma (CRC) is the third most common human cancer. Twist, a
basic helix-loop-helix (bHLH) transcription factor, is an epithelial-mesenchymal transition …

Purified recombinant human Chromogranin A N46 peptide with remarkable anticancer effect on human colon cancer cells

H Okasha, S Samir, SM Nasr - Bioorganic Chemistry, 2021 - Elsevier
Abstract Human Chromogranin A N46 (CGA-N46) is a weak cationic α-helical peptide with
wide-spectrum antibacterial, fungal, and anticancer activities. In this study, the recombinant …

Predictive factors of positive circumferential and longitudinal margins in early T3 colorectal cancer resection

MA Balbaa, N Elkady… - International journal of …, 2020 - Wiley Online Library
Background. Malignant involvement of circumferential resection margin (CRM) and
longitudinal resection margin (LRM) after surgical resection of colorectal cancer (CRC) are …