Gasdermin D (GSDMD)-mediated pyroptosis and downstream inflammation are important
self-protection mechanisms against stimuli and infections. Hosts can defend against …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve and
adapt after its emergence in late 2019. As the causative agent of the coronavirus disease …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve after its
emergence. Given its importance in viral infection and vaccine development, mutations in …

Aided by extensive protein mutations, the SARS-CoV-2 Omicron (B. 1.1. 529) variant
overtook the previously dominant Delta variant and rapidly spread around the world. It was …

As for all single-stranded, positive-sense RNA (+ RNA) viruses, intracellular RNA synthesis
relies on extensive remodeling of host cell membranes that leads to the formation of …

The unprecedented pandemic of SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2), which leads to COVID-19, is threatening global health. Over the last 2 years …

Pyroptosis is an active cell death process mediated by gasdermin family proteins including
Gasdermin A (GSDMA), Gasdermin B (GSDMB), Gasdermin C (GSDMC), Gasdermin D …

DNA G-quadruplex is a non-canonical secondary structure that could epigenetically regulate
gene expression. To investigate the regulating role of G-quadruplex, we devised an …

Autophagy is a highly conserved dynamic process by which cells deliver their contents to
lysosomes for degradation, thus ensuring cell homeostasis. In response to environmental …

Pyroptosis, a pro-inflammatory programmed cell death, has been implicated in the
pathogenesis of coronavirus disease 2019 and other viral diseases. Gasdermin family …