Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats
The tumor suppressor p53 is thought to play a key role in the maintenance of cell size and
homeostasis, but relatively little is known about its role in skeletal muscle. Based on its …
homeostasis, but relatively little is known about its role in skeletal muscle. Based on its …
Tenotomy-induced muscle atrophy is sex-specific and independent of NFκB
GA Meyer, S Thomopoulos, Y Abu-Amer, KC Shen - Elife, 2022 - elifesciences.org
The nuclear factor-κB (NFκB) pathway is a major thoroughfare for skeletal muscle atrophy
and is driven by diverse stimuli. Targeted inhibition of NFκB through its canonical mediator …
and is driven by diverse stimuli. Targeted inhibition of NFκB through its canonical mediator …
The proteasome regulates body weight and systemic nutrient metabolism during fasting
The ubiquitin-proteasome system (UPS) and the autophagy-lysosome pathway are the
primary means of degradation in mammalian tissues. We sought to determine the individual …
primary means of degradation in mammalian tissues. We sought to determine the individual …
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer
Aim To investigate systemic regulators of the cancer‐associated cachexia syndrome (CACS)
in a pre‐clinical model for lung cancer with the goal to identify therapeutic targets for tissue …
in a pre‐clinical model for lung cancer with the goal to identify therapeutic targets for tissue …
The desmin mutation R349P increases contractility and fragility of stem cell‐generated muscle micro‐tissues
Aims Desminopathies comprise hereditary myopathies and cardiomyopathies caused by
mutations in the intermediate filament protein desmin that lead to severe and often lethal …
mutations in the intermediate filament protein desmin that lead to severe and often lethal …
Tenotomy-induced muscle atrophy is sexspecific and independent of NF? B.
GA Meyer, S Thomopoulos, YA Amer, KC Shen - eLife, 2023 - search.ebscohost.com
The nuclear factor-KB (NFKB) pathway is a major thoroughfare for skeletal muscle atrophy
and is driven by diverse stimuli. Targeted inhibition of NFKB through its canonical mediator …
and is driven by diverse stimuli. Targeted inhibition of NFKB through its canonical mediator …
[HTML][HTML] Cloning and expression of murine Desmin gene and its bioinformatics analysis
Z Wen, LI Meng-ru, W Jing, Z Chuan-liang… - 南方农业 …, 2023 - nfnyxb.xml-journal.net
[Objective] To construct an eukaryotic/prokaryotic expression vector for murine type III
intermediate filamentary Desmin protein, to clarify the biological functions of murine Desmin …
intermediate filamentary Desmin protein, to clarify the biological functions of murine Desmin …