Photoreceptor cells and RPE contribute to the development of diabetic retinopathy

D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

Novel imaging biomarkers in diabetic retinopathy and diabetic macular edema

A Markan, A Agarwal, A Arora… - Therapeutic …, 2020 - journals.sagepub.com
Diabetic retinopathy is one of the major microvascular complications of diabetes mellitus.
The most common causes of vision loss in diabetic retinopathy are diabetic macular edema …

Early detection of diabetic retinopathy

H Safi, S Safi, A Hafezi-Moghadam… - Survey of ophthalmology, 2018 - Elsevier
Diabetic retinopathy (DR) is a primary cause of visual impairment worldwide. Diabetes
mellitus may be associated with ophthalmoscopically nonvisible neurovascular damage that …

Successful induction of diabetes in mice demonstrates no gender difference in development of early diabetic retinopathy

A Saadane, EM Lessieur, Y Du, H Liu, TS Kern - PLoS One, 2020 - journals.plos.org
Purpose Female mice have been found to be resistant to streptozotocin (STZ)-induced
diabetes, and pre-clinical research related to diabetic complications commonly omits …

Optical coherence tomography (angiography) biomarkers in the assessment and monitoring of diabetic macular edema

CI Suciu, VI Suciu, SD Nicoara - Journal of Diabetes Research, 2020 - Wiley Online Library
Retinopathy is one of the most severe diabetes‐related complications, and macular edema
is the major cause of central vision loss in patients with diabetes mellitus. Significant …

Beyond hyperglycemia, evidence for retinal neurodegeneration in metabolic syndrome

C Karaca, Z Karaca - Investigative ophthalmology & visual …, 2018 - iovs.arvojournals.org
Purpose: We evaluated the retinal effects of systemic metabolic changes clustered under the
umbrella of metabolic syndrome (MetS) in comparison with age-matched healthy subjects …

Correlation between choroidal vascularity index and outer retina in patients with diabetic retinopathy

P Sidorczuk, I Obuchowska, J Konopinska… - Journal of clinical …, 2022 - mdpi.com
The choroid supplies blood to the outer retina. We quantified outer retinal and choroidal
parameters to understand better the pathogenesis of diabetic retinopathy (DR) and diabetic …

Diabetic retinopathy: soluble and imaging ocular biomarkers

M Ferrara, A Loda, G Coco, P Grassi, S Cestaro… - Journal of Clinical …, 2023 - mdpi.com
Diabetic retinopathy (DR), the most common microvascular complication of diabetes
mellitus, represents the leading cause of acquired blindness in the working-age population …

Quantitative optical coherence tomography reveals rod photoreceptor degeneration in early diabetic retinopathy

D Le, T Son, JI Lim, X Yao - Retina, 2022 - journals.lww.com
Purpose: This study is to test the feasibility of optical coherence tomography (OCT) detection
of photoreceptor abnormality and to verify that the photoreceptor abnormality is rod …

Influence of OCT biomarkers on microperimetry intra-and interdevice repeatability in diabetic macular edema

H Stino, K Birner, L Hinterhuber, A Struppe… - Scientific Reports, 2024 - nature.com
To evaluate the intra-and interdevice repeatability of microperimetry (MP) assessments in
patients with diabetic macular edema (DME) two consecutive MP testings (45 fovea …