Neurologic impairments are usually irreversible as a result of limited regeneration in the
central nervous system. Therefore, based on the regenerative capacity of stem cells …

Stem cells are a versatile source for cell therapy. Their use is particularly significant for the
treatment of neurological disorders for which no definitive conventional medical treatment is …

We sought to obtain novel insights into schizophrenia pathogenesis by exploiting the
association between the disorder and chromosomal copy number (CNV) burden. We …

Purpose To examine the potential of NIH-maintained human embryonic stem cell (hESC)
lines TE03 and UC06 to differentiate into retinal progenitor cells (hESC-RPCs) using the …

Traumatic brain injury (TBI) in humans can result in permanent tissue damage and has been
linked to cognitive impairment that lasts years beyond the initial insult. Clinically effective …

The potential of human embryonic stem (ES) cells as experimental therapies for neuronal
replacement has recently received considerable attention. In view of the organization of the …

The retina is a very fine and layered neural tissue, which vitally depends on the preservation
of cells, structure, connectivity and vasculature to maintain vision. There is an urgent need to …

Although the majority of Alzheimer's disease (AD) cases are sporadic, about 5% of cases
are inherited in an autosomal dominant pattern as familial AD (FAD) and manifest at an early …

Traumatic brain injury (TBI) ranks as the leading cause of mortality and disability in the
young population worldwide. The annual US incidence of TBI in the general population is …

Both human pluripotent stem cells (hPSCs) from embryonic stem cells (hESCs) and induced
pluripotent stem cells (hiPSCs) have the potential ability to differentiate into many different …