Aims An algorithm for non‐invasive diagnosis of amyloid transthyretin cardiac amyloidosis
(ATTR‐CA) and novel disease‐modifying therapies have prompted an active search for CA …

Heart failure affects over 2.6 million women and 3.4 million men in the United States with
known sex differences in epidemiology, management, response to treatment, and outcomes …

The systemic amyloidoses are a broad spectrum of diseases that result from misfolding of
proteins that aggregate into b-sheet amyloid fibrils. Over 35 amyloidogenic precursor …

Abstract Introduction Hereditary transthyretin (ATTRv) amyloidosis is a rare, severe,
progressive, debilitating, and ultimately fatal disease caused by systemic deposition of …

Background Transthyretin amyloidosis (ATTR amyloidosis) is a rare, life-threatening disease
caused by the accumulation of variant or wild-type (ATTRwt amyloidosis) transthyretin …

Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is predominantly diagnosed in
men. The few available studies suggest affected women have a more favourable cardiac …

Protein aggregation and subsequent accumulation of insoluble amyloid fibrils with cross-β
structure is an intrinsic characteristic of amyloid diseases, ie, amyloidoses. Amyloid …

Background Transthyretin amyloidosis (ATTR amyloidosis) is a progressive, multisystemic,
life-threatening disease resulting from the deposition of variant or wild-type (ATTRwt …

Abstract Background Hereditary transthyretin amyloidosis (ATTRv amyloidosis) results from
pathogenic mutations in the transthyretin (TTR) gene. This analysis aimed to better …

Transthyretin cardiac amyloidosis (ATTR-CA) is a progressive disease characterized by the
deposition of abnormal transthyretin protein fibrils in the heart, leading to cardiac …