Cleavage of carbon–carbon bonds by radical reactions

P Sivaguru, Z Wang, G Zanoni, X Bi - Chemical Society Reviews, 2019 - pubs.rsc.org
In recent years, radical C–C bond cleavage reactions have been increasingly understood
and used to perform transformations that complement traditional ionic processes. However …

Recent advances in metal-free quinoline synthesis

GA Ramann, BJ Cowen - Molecules, 2016 - mdpi.com
The quinoline ring system is one of the most ubiquitous heterocycles in the fields of
medicinal and industrial chemistry, forming the scaffold for compounds of great significance …

Metal-free domino one-pot protocols for quinoline synthesis

JB Bharate, RA Vishwakarma, SB Bharate - RSC advances, 2015 - pubs.rsc.org
Quinoline is one of the most widely investigated scaffolds by synthetic chemists because of
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …

Synthesis of quinolines: A green perspective

VF Batista, DCGA Pinto, AMS Silva - ACS Sustainable Chemistry …, 2016 - ACS Publications
The quinoline scaffold is present in a vast number of natural compounds and
pharmacologically active substances, comprising a significant segment of the …

Magnetically supported ionic liquids: a sustainable catalytic route for organic transformations

R Gupta, M Yadav, R Gaur, G Arora, P Yadav… - Materials …, 2020 - pubs.rsc.org
From solvents to catalytic applications, ionic liquids have received burgeoning interest ever
since their discovery. They belong to a class of salt-like materials that have unusually low …

Discovery of Quinazolin-4(3H)-ones as NLRP3 Inflammasome Inhibitors: Computational Design, Metal-Free Synthesis, and in Vitro Biological Evaluation

M Abdullaha, S Mohammed, M Ali… - The Journal of …, 2019 - ACS Publications
NLRP3 inflammasome is an important therapeutic target for a number of human diseases.
Herein, computationally designed series of quinazolin-4 (3 H)-ones were synthesized using …

Recent progress in the synthesis of quinolines

DD Xuan - Current organic synthesis, 2019 - ingentaconnect.com
Background: Quinoline-containing compounds present in both natural and synthetic
products are an important class of heterocyclic compounds. Many of the substituted …

Synthesis of quinoline-fused 1-benzazepines through a Mannich-type reaction of a C, N-bisnucleophile generated from 2-aminobenzaldehyde and 2-methylindole

L Min, B Pan, Y Gu - Organic letters, 2016 - ACS Publications
Synthesis of Quinoline-Fused 1-Benzazepines through a Mannich-Type Reaction of a C,N-Bisnucleophile
Generated from 2-Aminobenzaldehyde and 2-Methylindole | Organic Letters ACS ACS …

Oxidant-Controlled C-sp2/sp3–H Cross-Dehydrogenative Coupling of N-Heterocycles with Benzylamines

R Sharma, M Abdullaha… - The Journal of Organic …, 2017 - ACS Publications
Oxidant controlled ionic liquid mediated cross-dehydrogenative coupling (CDC) of
benzylamines with N-heterocycles having sp2 or sp3 carbon resulted in the formation of C …

Metal-and solvent-free synthesis of 2-benzyl-3-arylquinoline using a pseudo-three-component reaction

S Faraz, M Kumar, AT Khan, S Ponneganti… - Tetrahedron …, 2023 - Elsevier
A highly efficient and straightforward synthetic protocol for the synthesis of 2-benzyl-3-
arylquinoline derivatives is developed from aryl amines and styrene oxides in the presence …