Berberine as a potential anticancer agent: A comprehensive review

A Rauf, T Abu-Izneid, AA Khalil, M Imran, ZA Shah… - Molecules, 2021 - mdpi.com
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial
amount of research has been conducted to date to establish the anticancer potential of BBR …

Berberine: new perspectives for old remedies

M Tillhon, LMG Ortiz, P Lombardi, AI Scovassi - Biochemical pharmacology, 2012 - Elsevier
Chemical compounds derived from plants have been used since the origin of human beings
to counteract a number of diseases. Among them, the natural isoquinoline alkaloid …

Berberine for gastric cancer prevention and treatment: Multi-step actions on the Correa's cascade underlie its therapeutic effects

Q Liu, J Tang, S Chen, S Hu, C Shen, J Xiang… - Pharmacological …, 2022 - Elsevier
Gastric carcinoma (GC) is a complex multifactorial disease occurring as sequential events
commonly referred to as the Correa's cascade, a stepwise progression from non-active or …

Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations

J Tang, Y Feng, S Tsao, N Wang, R Curtain… - Journal of …, 2009 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Coptidis Rhizoma (Huanglian) and its major
component, berberine, have drawn extensive attention toward their antineoplastic effects in …

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs

Y Sun, K Xun, Y Wang, X Chen - Anti-cancer drugs, 2009 - journals.lww.com
Natural products represent a rich reservoir of potential small chemical molecules exhibiting
antiproliferation and anticancer properties. An example is berberine, a protoberberine …

Berberine: an important emphasis on its anticancer effects through modulation of various cell signaling pathways

SA Almatroodi, MA Alsahli, AH Rahmani - Molecules, 2022 - mdpi.com
Cancer is the most commonly diagnosed type of disease and a major cause of death
worldwide. Despite advancement in various treatment modules, there has been little …

Berberine hydrochloride: anticancer activity and nanoparticulate delivery system

W Tan, Y Li, M Chen, Y Wang - International journal of …, 2011 - Taylor & Francis
Background Berberine hydrochloride is a conventional component in Chinese medicine,
and is characterized by a diversity of pharmacological effects. However, due to its …

Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression

HS Kim, MJ Kim, EJ Kim, Y Yang, MS Lee… - Biochemical …, 2012 - Elsevier
Berberine is clinically important natural isoquinoline alkaloid that affects various biological
functions, such as cell proliferation, migration and survival. The activation of AMP-activated …

Berberine improves chemo-sensitivity to cisplatin by enhancing cell apoptosis and repressing PI3K/AKT/mTOR signaling pathway in gastric cancer

Y Kou, B Tong, W Wu, X Liao, M Zhao - Frontiers in pharmacology, 2020 - frontiersin.org
Gastric cancer is one of the most common malignancies ranks as the second leading cause
of cancer-related mortality in the world. Cisplatin (DDP) is commonly used for gastric cancer …

Berberine: A Traditional Natural Product With Novel Biological Activities.

Q Hou, WJ He, YS Wu, HJ Hao… - … Therapies in Health …, 2020 - search.ebscohost.com
Context• Having been used for thousands of years to treat gastrointestinal diseases, the
natural isoquinoline alkaloid, berberine, has exhibited a wide spectrum of biochemical and …