Paracoccidioides brasiliensis and P. lutzii are etiologic agents of paracoccidioidomycosis
(PCM), an important endemic mycosis in Latin America. During its evolution, these fungi …

Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …

The emergence of distinct populations of Cryptococcus gattii in the temperate North
American Pacific Northwest (PNW) was surprising, as this species was previously thought to …

Segmented filamentous bacteria (SFB) are noncultivable commensals inhabiting the gut of
various vertebrate species and have been shown to induce Th17 cells in mice. We present …

Iron is an essential nutrient for all organisms. For pathogenic fungi, iron is essential for the
success of infection. Thus, these organisms have developed high affinity iron uptake …

The ability of Paracoccidioides to defend itself against reactive oxygen species (ROS)
produced by host effector cells is a prerequisite to survive. To counteract these radicals …

Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with
Paracoccidioides brasiliensis and P. lutzii being the causal agents of this disorder. Several …

Background Paracoccidioides brasiliensis is a human thermal dimorphic pathogenic fungus.
Survival of P. brasiliensis inside the host depends on the adaptation of this fungal pathogen …

Background Hypoxic microenvironments are generated during fungal infection. It has been
described that to survive in the human host, fungi must also tolerate and overcome in vivo …

Glycoprotein gp43 is an immunodominant diagnostic antigen for paracoccidioidomycosis
caused by Paracoccidioides brasiliensis. It is abundantly secreted in isolates such as …