Skin makes an excellent site for drug and vaccine delivery due to easy accessibility, immuno-
surveillance functions, avoidance of macromolecular degradation in the gastrointestinal tract …

Inlet flow distortion is expected to play a major role in future aircraft architectures where
complex air induction systems are required to couple the engine with the airframe. The …

A unique form of needle-free drug and vaccine delivery is under investigation. The principle
of the concept is to accelerate pharmaceuticals in particle form to a momentum sufficient to …

New insights in vaccine development, the need for safe, economic and efficient vaccine
administration and the increasing mechanistic knowledge of immune responses induced by …

Introduction Microneedles are emerging as a promising technology for vaccine delivery, with
numerous advantages over traditional needle and syringe methods. Preclinical studies have …

Many vaccines make use of an adjuvant to achieve stronger immune responses.
Alternatively, potent immune responses have also been generated by replacing the …

We investigate the flow physics of non-equilibrium gases in interaction with solid particles in
a microscale shock tube and the collection efficiency in the jet impingement on a permeable …

A challenge in epidermal DNA vaccination is the efficient and targeted delivery of
polynucleotides to immunologically sensitive Langerhans cells. This paper investigates this …

An experimental study to examine the hydrodynamic performance and start-up phase of
liquid jets for needle-free injection was performed. With the use of high-speed videography …

Context: Gene guns have been used to deliver deoxyribonucleic acid (DNA) loaded micro-
particle and breach the muscle tissue to target cells of interest to achieve gene transfection …