Colorectal cancer: from risk factors to oncogenesis

VA Ionescu, G Gheorghe, N Bacalbasa, AL Chiotoroiu… - Medicina, 2023 - mdpi.com
Colorectal cancer is the second leading cause of cancer-related mortality worldwide.
Numerous pathophysiological mechanisms, such as abnormal cell proliferation, cell …

[HTML][HTML] Hereditary colorectal Cancer syndromes and inflammatory bowel diseases: risk management and surveillance strategies

L Brandaleone, A Dal Buono, R Gabbiadini… - Cancers, 2024 - mdpi.com
Simple Summary Hereditary colorectal cancer syndromes (HCCS) and inflammatory bowel
disease (IBD) carry a high risk of developing colorectal cancer (CRC). The co-occurrence of …

Inflammatory bowel disease-associated colorectal cancer epidemiology and outcomes: an English population-based study

RJ Birch, N Burr, V Subramanian… - Official journal of the …, 2022 - journals.lww.com
METHODS: Using population data from the English National Health Service held in the CRC
data repository, all CRCs with and without prior diagnosis of IBD (Crohn's, ulcerative colitis …

A novel anoikis-related gene prognostic signature and its correlation with the immune microenvironment in colorectal cancer

Y Xiao, H Zhou, Y Chen, L Liu, Q Wu, H Li, P Lin… - Frontiers in …, 2023 - frontiersin.org
Background: Anoikis is a type of apoptosis associated with cell detachment. Resistance to
anoikis is a focal point of tumor metastasis. This study aimed to explore the relationship …

Alterations in p53, microsatellite stability and lack of MUC5AC expression as molecular features of colorectal carcinoma associated with inflammatory bowel disease

M Gené, M Cuatrecasas, I Amat, JA Veiga… - International Journal of …, 2023 - mdpi.com
Colitis-associated colorectal carcinoma (CAC) occurs in inflammatory bowel disease (IBD)
because of the “chronic inflammation-dysplasia-cancer” carcinogenesis pathway …

Obesity and early-onset colorectal cancer risk: emerging clinical evidence and biological mechanisms

P Xu, Z Tao, H Yang, C Zhang - Frontiers in Oncology, 2024 - frontiersin.org
Early-onset colorectal cancer (EOCRC) is indicated as a global burden. EOCRC The
disease is associated with specific molecular and clinical features. As Obesity is a well …

Hereditary colorectal cancer syndromes and inflammatory bowel disease: results from a registry-based study

S Lauricella, MT Ricci, GE Tontini, F Cavallaro… - International Journal of …, 2025 - Springer
Purpose In this study, we investigated the progression of high-grade dysplasia (HGD)/CRC
in patients with hereditary colorectal cancer syndromes (HCSS) and concomitant …

Dye Chromoendoscopy Outperforms High-Definition White Light Endoscopy in Dysplasia Detection for IBD Patients: An Updated Meta-analysis of Randomized …

MFH Mohamed, D Marino, K Elfert… - Official journal of the …, 2022 - journals.lww.com
Objective Whether dye spray chromoendoscopy (DCE) adds value in surveillance
colonoscopy with high-definition (HD) scopes remains controversial. This updated meta …

Targeting colorectal cancer with Herba Patriniae and Coix seed: Network pharmacology, molecular docking, and in vitro validation

CL Wang, BW Yang, XY Wang, X Chen… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Herba Patriniae and Coix seed (HC) constitute a widely utilized drug
combination in the clinical management of colorectal cancer (CRC) that is known for its …

[HTML][HTML] 早发性与晚发性结直肠癌临床特征比较及预后的分析

龙贤, 王悦, 简梓晴, 何琼 - 世界华人消化杂志, 2024 - wjgnet.com
结直肠癌(colorectal cancer, CRC) 是全球常见的消化系肿瘤, 发病率位于世界第3,
病死率位居世界第2, 近年来结直肠癌总的发病率及病死率有所下降, 但早发性结直肠癌(early …