Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases

M Mehta, D Tewari, G Gupta, R Awasthi, H Singh… - Chemico-biological …, 2019 - Elsevier
Oligonucleotide-based therapies are advanced novel interventions used in the management
of various respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease …

Emerging trends in the novel drug delivery approaches for the treatment of lung cancer

P Sharma, M Mehta, DS Dhanjal, S Kaur… - Chemico-biological …, 2019 - Elsevier
Cancer is one of the major diseases that cause a high number of deaths globally. Of the
major types of cancers, lung cancer is known to be the most chronic form of cancer in the …

The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress

K Dua, R Wadhwa, G Singhvi, V Rapalli… - Drug development …, 2019 - Wiley Online Library
Lung diseases are the leading cause of mortality worldwide. The currently available
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …

Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update

M Mehta, DS Dhanjal, KR Paudel, B Singh… - …, 2020 - Springer
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: an emerging need for novel drug delivery systems

K Dua, V Malyla, G Singhvi, R Wadhwa… - Chemico-biological …, 2019 - Elsevier
Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …

[HTML][HTML] Nano drug delivery in intracellular bacterial infection treatments

SM Hosseini, M Taheri, F Nouri, A Farmani… - Biomedicine & …, 2022 - Elsevier
The present work aimed to review the potential mechanisms used by macrophages to kill
intracellular bacteria, their entrance to the cell, and mechanisms of escape of cellular …

Antiproliferative effects of boswellic acid-loaded chitosan nanoparticles on human lung cancer cell line A549

N Solanki, M Mehta, DK Chellappan… - Future medicinal …, 2020 - Taylor & Francis
Aim: In the present study boswellic acids-loaded chitosan nanoparticles were synthesized
using ionic gelation technique. The influence of independent variables were studied and …

Interactions with the macrophages: an emerging targeted approach using novel drug delivery systems in respiratory diseases

M Mehta, N Sharma, M Vyas, N Khurana… - Chemico-biological …, 2019 - Elsevier
Macrophages are considered as the most flexible cells of the hematopoietic system that are
distributed in the tissues to act against pathogens and foreign particles. Macrophages are …

Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics

YY Tan, PK Yap, GLX Lim, M Mehta, Y Chan… - Chemico-biological …, 2020 - Elsevier
Cancer continues to be one of the most challenging diseases to be treated and is one of the
leading causes of deaths around the globe. Cancers account for 13% of all deaths each …

Pulmonary targeting of inhalable moxifloxacin microspheres for effective management of tuberculosis

B Vishwa, A Moin, DV Gowda, SMD Rizvi… - Pharmaceutics, 2021 - mdpi.com
In the present study, the objective was to attain a localized lung delivery of an anti-tubercular
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …