Nuclei as mechanical bumpers during epithelial remodeling

NF de Leeuw, R Budhathoki, LJ Russell… - Journal of Cell …, 2024 - rupress.org
The morphogenesis of developing tissues relies on extensive cellular rearrangements in
shape, position, and identity. A key process in reshaping tissues is cell intercalation-driven …

Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation

HA Crellin, C Zhu, G Serrano-Nájera, A Race… - bioRxiv, 2024 - biorxiv.org
How do cellular forces propagate through tissue to allow large-scale morphogenetic events?
To investigate this question, we used an in vivo optogenetic approach to reversibly …