Update in biomolecular and genetic bases of bicuspid aortopathy

A Junco-Vicente, Á del Río-García, M Martín… - International journal of …, 2021 - mdpi.com
Bicuspid aortic valve (BAV) associated with aortopathy is the most common congenital heart
disease in the general population. Far from being a simple harmless valve malformation, it …

Patients with bicuspid aortopathy and aortic dilatation

F Nappi, O Giacinto, M Lusini, M Garo… - Journal of Clinical …, 2022 - mdpi.com
(1) Background: Bicuspid aortic valve (BAV) is the most frequent congenital cardiac disease.
Alteration of ascending aorta diameter is a consequence of shear stress alterations due to …

Deep learning approach for the segmentation of aneurysmal ascending aorta

A Comelli, N Dahiya, A Stefano, V Benfante… - Biomedical engineering …, 2021 - Springer
Diagnosis of ascending thoracic aortic aneurysm (ATAA) is based on the measurement of
the maximum aortic diameter, but size is not a good predictor of the risk of adverse events …

Shear stress and aortic strain associations with biomarkers of ascending thoracic aortic aneurysm

S Pasta, V Agnese, A Gallo, F Cosentino… - The Annals of thoracic …, 2020 - Elsevier
Background This study aims to investigate the association of wall shear stress (WSS) and
aortic strain with circulating biomarkers including matrix metalloproteinases (MMP), tissue …

Deciphering ascending thoracic aortic aneurysm hemodynamics in relation to biomechanical properties

G De Nisco, P Tasso, K Calò, V Mazzi, D Gallo… - Medical engineering & …, 2020 - Elsevier
The degeneration of the arterial wall at the basis of the ascending thoracic aortic aneurysm
(ATAA) is a complex multifactorial process, which may lead to clinical complications and …

[HTML][HTML] Multi-pollutant exposure profiles associated with breast cancer risk: A Bayesian profile regression analysis in the French E3N cohort

C Giampiccolo, A Amadou, T Coudon, D Praud… - Environment …, 2024 - Elsevier
Background Human exposure to air pollution involves complex mixtures of multiple
correlated air pollutants. To date, very few studies have assessed the combined effects of …

Statistical shape analysis of ascending thoracic aortic aneurysm: correlation between shape and biomechanical descriptors

F Cosentino, GM Raffa, G Gentile, V Agnese… - Journal of personalized …, 2020 - mdpi.com
An ascending thoracic aortic aneurysm (ATAA) is a heterogeneous disease showing
different patterns of aortic dilatation and valve morphologies, each with distinct clinical …

Risk stratification in bicuspid aortic valve aortopathy: emerging evidence and future perspectives

A Della Corte, HI Michelena, A Citarella, E Votta… - Current Problems in …, 2021 - Elsevier
The current management of aortic dilatation associated with congenital bicuspid aortic valve
(bicuspid aortic valve aortopathy) is based on dimensional parameters (diameter of the …

MicroRNAs fingerprint of bicuspid aortic valve

J Sabatino, Z Wicik, S De Rosa, C Eyileten… - Journal of Molecular and …, 2019 - Elsevier
Aortic valve tissue is largely exposed to high blood flow. Cells belonging to aortic valve
tissues are able to detect and respond to flow conditions changes. Bicuspid aortic valve …

An overview of the molecular mechanisms underlying development and progression of bicuspid aortic valve disease

CR Balistreri, M Forte, E Greco, F Paneni… - Journal of molecular and …, 2019 - Elsevier
Bicuspid aortic valve (BAV) is a common congenital heart malformation frequently
associated with the development of aortic valve diseases and severe aortopathy, such as …