AIM The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial
Fibrillation” provides recommendations to guide clinicians in the treatment of patients with …

Abstract Background and Aims Residual leaks are not infrequent after left atrial appendage
occlusion. However, there is still uncertainty regarding their prognostic implications. The aim …

Exclusion of the left atrial appendage to reduce thromboembolic risk related to atrial
fibrillation was first performed surgically in 1949. Over the past 2 decades, the field of …

Background Intracardiac echocardiography (ICE) is increasingly used to guide left atrial
appendage closure (LAAC). Objectives The aim of this study was to investigate the efficacy …

The field of left atrial appendage occlusion is rapidly evolving. However, several issues
remain including the limited randomized efficacy data, peri-device leak, device-related …

Nonvalvular atrial fibrillation is a common rhythm disorder of middle-aged to older adults that
can cause ischemic strokes and systemic embolism. Lifelong use of oral anticoagulants …

Abstract Background The Amulet (Abbott) left atrial appendage occluder investigational
device exemption trial is the largest randomized trial evaluating the safety and effectiveness …

Background When performing transcatheter left atrial appendage (LAA) closure, peridevice
leaks and device-related thrombus (DRT) have been associated with worse clinical …

Background Peridevice leak (PDL) is a limitation of left atrial appendage occlusion.
Objectives The aim of this study was to assess the incidence of and outcomes associated …

Background The impact of preprocedure imaging on the safety and effectiveness of left atrial
appendage occlusion (LAAO) remains unclear. Objectives This study sought to determine …