AB Hart, HR Kranzler - Alcoholism: Clinical and Experimental …, 2015 - Wiley Online Library
Background Alcohol dependence (AD) is a complex psychiatric disorder and a significant public health problem. Twin and family‐based studies have consistently estimated its …
We report a GWAS of alcohol dependence (AD) in European-American (EA) and African- American (AA) populations, with replication in independent samples of EAs, AAs and …
J Gelernter, R Sherva, R Koesterer, L Almasy… - Molecular …, 2014 - nature.com
We report a genome-wide association study (GWAS) for cocaine dependence (CD) in three sets of African-and European-American subjects (AAs and EAs, respectively) to identify …
A Agrawal, SJ Brislin, KK Bucholz… - Genes, Brain and …, 2023 - Wiley Online Library
Alcohol use disorders (AUD) are commonly occurring, heritable and polygenic disorders with etiological origins in the brain and the environment. To outline the causes and …
D Lai, L Wetherill, S Bertelsen, CE Carey… - Genes, Brain and …, 2019 - Wiley Online Library
Genome‐wide association studies (GWAS) of alcohol dependence (AD) have reliably identified variation within alcohol metabolizing genes (eg, ADH1B) but have inconsistently …
In this project, we aimed to bring large-scale gene-identification findings into a developmental psychopathology framework. Using a family-based sample, we tested …
Autism imposes a major impediment to childhood development and a huge emotional and financial burden on society. In recent years, there has been rapidly accumulating genetic …
JN McClintick, X Xuei, JA Tischfield, A Goate, T Foroud… - Alcohol, 2013 - Elsevier
The chronic high-level alcohol consumption seen in alcoholism leads to dramatic effects on the hippocampus, including decreased white matter, loss of oligodendrocytes and other glial …
EE Quillen, XD Chen, L Almasy, F Yang… - American Journal of …, 2014 - Wiley Online Library
Alcohol dependence (AD) is a moderately heritable phenotype with a small number of known risk genes mapped via linkage or candidate gene studies. We considered 313 males …