Staphylococcus aureus is responsible for a series of infections occurring in both human and
animal hosts. S. aureus SA1199B is a strain resistant to hydrophilic fluoroquinolone due to …

Six 2'-hydroxychalcones were synthesized and characterized by NMR, FT-Raman, ATR-
FTIR, and UV-Vis. These chalcones alone and in combination with the ciprofloxacin …

Chalcones and their derivatives have been widely studied at research institutions and
industries, in order to verify their biological properties against various diseases. In this work …

A large number of infections are caused by multi-resistant bacteria worldwide, adding up to
a figure of around 700,000 deaths per year. Because of that many strategies are being …

The increased resistance of microorganisms to antimicrobial drugs makes it necessary to
search for new active compounds, such as chalcones. Their simple chemical structure …

Bacterial resistance induced by efflux pumps is a frequent concern in clinical treatments
involving multi-resistant bacteria. Staphylococcus aureus is a microorganism responsible for …

Chalcones are open-chain flavonoids characterized by two aromatic rings joined by a three-
carbon α, β-unsaturated carbonyl system. Over the last several years, chalcones have …

The purpose of the current investigation was to produce cinammaldehyde-based chalcone
derivatives (3a–k) to evaluate their potential effectiveness as antioxidant and inhibitory …

With the spread of bacterial resistance against clinically used antibiotics, natural plant-
derived products are being studied as new sources of antibacterial molecules. Manilkara …

Chagas disease is a disease that is emerging in North America and Europe countries.
Benznidazole is the main drug available, but it has high toxicity and low efficacy in the …