Though single tumor immunotherapy and radiotherapy have significantly improved the
survival rate of tumor patients, there are certain limitations in overcoming tumor metastasis …

Both T-cell deprivation and insufficient tumor immunogenicity seriously hinder the efficacy of
immune-mediated tumor destruction in melanoma. In this work, an amphiphilic polyethylene …

As nano-sized materials prepared by isolating, disrupting and extruding cell membranes,
cellular vesicles are emerging as a novel vehicle for immunotherapeutic drugs to activate …

Cancer vaccines represent among the most promising strategies in the battle against
cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the …

The in situ vaccine effect of radiation therapy (RT) has been shown to be limited in both
preclinical and clinical settings, possibly due to the inadequacy of RT alone to stimulate in …

The buccal region of the oral cavity is an attractive target for administration of the drug of
choice, particularly in overcoming deficiencies associated with the latter mode of …

The natural world has provided a host of materials and inspiration for the field of
nanomedicine. By taking design cues from naturally occurring systems, the …

There has been a rapid development of biomimetic platforms using cell membranes as
nanocarriers to camouflage nanoparticles for enhancing bio-interfacial capabilities. Various …

Introduction Combining CpG oligodeoxynucleotides with anti-OX40 agonist antibody (CpG+
OX40) is able to generate an effective in situ vaccine in some tumor models, including the …

Peninsular India is a unique region with major mountain ranges that govern regional
atmospheric circulation and precipitation variability, the monsoons, and regional geology at …