The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

DNA hydrogel-based gene editing and drug delivery systems

F Mo, K Jiang, D Zhao, Y Wang, J Song… - Advanced Drug Delivery …, 2021 - Elsevier
Deoxyribonucleic acid (DNA) is a promising synthesizer for precisely constructing almost
arbitrary geometry in two and three dimensions. Among various DNA-based soft materials …

Applications of catalytic hairpin assembly reaction in biosensing

J Liu, Y Zhang, H Xie, L Zhao, L Zheng, H Ye - Small, 2019 - Wiley Online Library
Nucleic acids are considered as perfect programmable materials for cascade signal
amplification and not merely as genetic information carriers. Among them, catalytic hairpin …

DNA supramolecular assembly on micro/nanointerfaces for bioanalysis

C Yao, J Ou, J Tang, D Yang - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Facing increasing demand for precision medicine, materials chemistry systems
for bioanalysis with accurate molecular design, controllable structure, and adjustable …

Advanced bottom‐up engineering of living architectures

VM Gaspar, P Lavrador, J Borges… - Advanced …, 2020 - Wiley Online Library
Bottom‐up tissue engineering is a promising approach for designing modular biomimetic
structures that aim to recapitulate the intricate hierarchy and biofunctionality of native human …

DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation

X Huang, JZ Williams, R Chang, Z Li, CE Burnett… - Nature …, 2021 - nature.com
Biomaterials can improve the safety and presentation of therapeutic agents for effective
immunotherapy, and a high level of control over surface functionalization is essential for …

[HTML][HTML] Nature-derived materials for the fabrication of functional biodevices

S Pradhan, AK Brooks, VK Yadavalli - Materials Today Bio, 2020 - Elsevier
Nature provides an incredible source of inspiration, structural concepts, and materials
toward applications to improve the lives of people around the world, while preserving …

Smart and functionalized development of nucleic acid‐based hydrogels: Assembly strategies, recent advances, and challenges

Y Zhang, L Zhu, J Tian, L Zhu, X Ma, X He… - Advanced …, 2021 - Wiley Online Library
Nucleic acid‐based hydrogels that integrate intrinsic biological properties of nucleic acids
and mechanical behavior of their advanced assemblies are appealing bioanalysis and …

Harnessing nucleic acids nanotechnology for bone/cartilage regeneration

Y Han, L Cao, G Li, F Zhou, L Bai, J Su - Small, 2023 - Wiley Online Library
The effective regeneration of weight‐bearing bone defects and critical‐sized cartilage
defects remains a significant clinical challenge. Traditional treatments such as autologous …