Epstein-Barr virus (EBV), a gamma-1 herpesvirus, is carried as a life-long asymptomatic
infection by the great majority of individuals in all human populations. Yet this seemingly …

Epstein–Barr virus (EBV) was the first tumour virus identified in humans. The virus is
primarily associated with lymphomas and epithelial cell cancers. These tumours express …

It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

Persistent infection by EBV is explained by the germinal center model (GCM) which provides
a satisfying and currently the only explanation for EBVs disparate biology. Since the GCM …

Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

This review of the life cycle of the Epstein–Barr virus (EBV) explains how EBV establishes
lifelong infection in a host with protective immunity against the virus. The authors also …

Hodgkin's lymphoma was first described in 1832. The aetiology of this lymphoma, however,
remained enigmatic for a long time. Only within the past 10 years has the B-cell nature of the …

Since the discovery in 1964 of the Epstein–Barr virus (EBV) in African Burkitt lymphoma, this
virus has been associated with a remarkably diverse range of cancer types. Because EBV …

Epstein–Barr virus (EBV) is an extremely successful virus, infecting more than 90% of the
human population worldwide. After primary infection, the virus persists for the life of the host …

Highlights•We summarize and update the germinal center model of Epstein–Barr virus
persistence.•We discuss the weaknesses and strengths of alternate models.•The role of …