Role of vascular endothelial growth factor (VEGF) in human embryo implantation: clinical implications

X Guo, H Yi, TC Li, Y Wang, H Wang, X Chen - Biomolecules, 2021 - mdpi.com
Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that plays a
critical role in various physiological and pathological processes. VEGF also contributes to …

Recurrent pregnancy loss etiology, risk factors, diagnosis, and management. Fresh look into a full box

A Turesheva, G Aimagambetova, T Ukybassova… - Journal of clinical …, 2023 - mdpi.com
Recurrent pregnancy loss is a complex health challenge with no universally accepted
definition. Inconsistency in definitions involves not only the number of spontaneous …

The role of oxidative stress in patients with recurrent pregnancy loss: a review

VA Zejnullahu, VA Zejnullahu, E Kosumi - Reproductive Health, 2021 - Springer
Background Recurrent pregnancy loss (RPL) presents one of the main problems in the field
of reproductive medicine, due to the unknown etiology in 50% of cases, as well as limited …

Role of microRNAs in trophoblast invasion and spiral artery remodeling: implications for preeclampsia

H Hayder, Y Shan, Y Chen, JA O'Brien… - Frontiers in Cell and …, 2022 - frontiersin.org
It is now well-established that microRNAs (miRNAs) are important regulators of gene
expression. The role of miRNAs in placental development and trophoblast function is …

MicroRNA-16 inhibits feto-maternal angiogenesis and causes recurrent spontaneous abortion by targeting vascular endothelial growth factor

Y Zhu, H Lu, Z Huo, Z Ma, J Dang, W Dang, L Pan… - Scientific reports, 2016 - nature.com
Recurrent spontaneous abortion (RSA) is a common health problem that affects women of
reproductive age. Recent studies have indicated that microRNAs are important factors in …

Placental growth factor (PlGF) as an angiogenic/inflammatory switcher: lesson from early pregnancy losses

HR Nejabati, Z Latifi, T Ghasemnejad… - Gynecological …, 2017 - Taylor & Francis
Placental growth factor (PlGF) is an angiogenic factor which belongs to vascular endothelial
growth factor (VEGF) family. In addition to the angiogenic function of PlGF, in some …

Genetics of recurrent pregnancy loss among Iranian population

M Moghbeli - Molecular Genetics & Genomic Medicine, 2019 - Wiley Online Library
Background Recurrent pregnancy loss (RPL) is one of the most common reproductive
disorders which is defined as the occurrence of recurrent miscarriage before 24 weeks of …

Reduced expressions of connexin 43 and VEGF in the first-trimester tissues from women with recurrent pregnancy loss

X He, Q Chen - Reproductive Biology and Endocrinology, 2016 - Springer
Abstract Background Approximately 45–50% of the recurrent pregnancy loss (RPL) remain
(s) unexplained that challenges its clinical management. Formation and development of …

Association of vascular endothelial growth factors (VEGFs) with recurrent miscarriage: a systematic review of the literature

N Abu-Ghazaleh, S Brennecke, P Murthi… - International Journal of …, 2023 - mdpi.com
Recurrent miscarriage (RM) can be defined as two or more consecutive miscarriages before
20 weeks' gestation. Vascular endothelial growth factors (VEGFs) play an important role in …

H19 regulates angiogenic capacity of extravillous trophoblasts by H19/miR-106a-5p/VEGFA axis

H Zeng, D He, H Xie, Y Zhao, Z Peng, H Deng… - Archives of Gynecology …, 2020 - Springer
Purpose To investigate the role and underlying mechanism of H19 in regulating angiogenic
capacity of extravillous trophoblasts. Methods Gain and loss of function experiments were …