State-of-the-art computational models of circle of willis with physiological applications: a review

H Liu, D Wang, X Leng, D Zheng, F Chen… - Ieee …, 2020 - ieeexplore.ieee.org
Background: Various computational models of the circle of Willis (CoW) have been
developed to non-invasively estimate the blood flow and hemodynamic parameters in …

Multi-Dimensional Modeling of Cerebral Hemodynamics: A Systematic Review

J Korte, ES Klopp, P Berg - Bioengineering, 2024 - mdpi.com
The Circle of Willis (CoW) describes the arterial system in the human brain enabling the
neurovascular blood supply. Neurovascular diseases like intracranial aneurysms (IAs) can …

Non-periodicity of blood flow and its influence on wall shear stress in the carotid artery bifurcation: An in vivo measurement-based computational study

X Zhou, L Yin, L Xu, F Liang - Journal of Biomechanics, 2020 - Elsevier
Although arterial blood flow is physiologically non-periodic under resting conditions,
periodic flow assumption has been widely adopted in most hemodynamic studies. So far, it …

Deep-learning-based real-time individualization for reduce-order haemodynamic model

B Li, G Li, J Liu, H Sun, C Wen, Y Yang, A Qiao… - Computers in Biology …, 2024 - Elsevier
The reduced-order lumped parameter model (LPM) has great computational efficiency in
real-time numerical simulations of haemodynamics but is limited by the accuracy of patient …

Numerical simulation of blood flow in aorta with dilation: a comparison between laminar and LES modeling methods

L Xu, T Yang, L Yin, Y Kong… - … in Engineering & …, 2020 - ingentaconnect.com
Computational modeling methods have been increasingly employed to quantify aortic
hemodynamic parameters that are challenging to in vivo measurements but important for the …

Combination of morphological and hemodynamic parameters for assessing the rupture risk of intracranial aneurysms: a retrospective study on mirror middle cerebral …

S Xin, Y Chen, B Zhao, F Liang - Journal of …, 2022 - asmedigitalcollection.asme.org
Discordant findings were frequently reported by studies dedicated to exploring the
association of morphological/hemodynamic factors with the rupture of intracranial …

[PDF][PDF] A computational study on the influence of aortic valve disease on hemodynamics in dilated aorta

L Xu, L Yin, Y Liu, F Liang - Math. Biosci. Eng, 2020 - researchgate.net
A computational hemodynamics method was employed to investigate how the morphotype
and functional state of aortic valve would affect the characteristics of blood flow in aortas with …

Hemodynamics of Circle of Willis Having Hypoplastic/Stenotic Anterior Cerebral Artery A1 Segment

HM Menon, T Dolkar, J Sudhir… - … and Science in …, 2025 - asmedigitalcollection.asme.org
This study utilizes computational tools to analyze the hemodynamic effects of a
hypoplastic/stenotic A1 segment in the anterior cerebral artery (ACA) on the circle of Willis …

[HTML][HTML] Computational methods applied to analyze the hemodynamic effects of flow-diverter devices in the treatment of cerebral aneurysms: current status and future …

L Xu, B Zhao, X Liu, F Liang - Medicine in Novel Technology and Devices, 2019 - Elsevier
Flow diverter (FD) devices have been widely employed to treat cerebral aneurysms. Despite
the well-documented clinical benefits, considerable inter-patient variability in clinical …

[HTML][HTML] 动脉内皮血流动力学微环境建模分析和体外模拟方法与技术研究进展

覃开蓉, 梁夫友, 那景童 - 实验流体力学, 2020 - pubs.cstam.org.cn
动脉内皮微环境中的血压, 壁面剪应力和牵张应力等血流动力学参量在维持内皮的正常生理功能
中扮演着至关重要的角色. 在体(in vivo) 动脉内皮血流动力学微环境的建模分析与体外(in vitro) …