A Pecci, X Ma, A Savoia, RS Adelstein - Gene, 2018 - Elsevier
The MYH9 gene encodes the heavy chain of non-muscle myosin IIA, a widely expressed cytoplasmic myosin that participates in a variety of processes requiring the generation of …
O Miltiadous, M Hou, JB Bussel - Blood, The Journal of the …, 2020 - ashpublications.org
Immune thrombocytopenia (ITP) is the most common acquired thrombocytopenia after chemotherapy-induced thrombocytopenia. Existing guidelines describe the management …
P Noris, G Biino, A Pecci, E Civaschi… - Blood, The Journal …, 2014 - ashpublications.org
Abnormalities of platelet size are one of the distinguishing features of inherited thrombocytopenias (ITs), and evaluation of blood films is recommended as an essential step …
SK Westbury, E Turro, D Greene, C Lentaigne… - Genome medicine, 2015 - Springer
Background Heritable bleeding and platelet disorders (BPD) are heterogeneous and frequently have an unknown genetic basis. The BRIDGE-BPD study aims to discover new …
C Zaninetti, P Gresele, A Bertomoro, C Klersy… - …, 2019 - pmc.ncbi.nlm.nih.gov
Patients with inherited thrombocytopenias often require platelet transfusions to raise their platelet count before surgery or other invasive procedures; moreover, subjects with clinically …
B Saposnik, S Binard, O Fenneteau… - Molecular genetics & …, 2014 - Wiley Online Library
MYH 9‐Related Disorders are a group of rare autosomal dominant platelet disorders presenting as nonsyndromic forms characterized by macrothrombocytopenia with giant …
V Palma-Barqueros, L Bury, S Kunishima… - Blood …, 2021 - ashpublications.org
Abstract β1-Tubulin plays a major role in proplatelet formation and platelet shape maintenance, and pathogenic variants in TUBB1 lead to thrombocytopenia and platelet …
C Zaninetti, A Greinacher - Journal of Clinical Medicine, 2020 - mdpi.com
Inherited platelet disorders (IPDs) are rare diseases featured by low platelet count and defective platelet function. Patients have variable bleeding diathesis and sometimes …
In this issue we highlight a very topical and timely review by Noris and colleagues entitled “New roles for MPV measurement in clinical practice?”[1], and discuss our newly proposed …